Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989324 | 0.84 | GABRA1 (0.43) | DHODHGABRA1GABRB2S1PR1MEN1 | |
| SCHEMBL12074723 | 0.76 | KIF11 (0.42) | TNFS1PR1MEN1KMT2A | |
| SCHEMBL20902563 | 0.76 | MEN1 (0.42) | TNFMEN1POLBMAPTKMT2A | |
| SCHEMBL21617927 | 0.75 | ALDH1A1 (0.45) | TNFMEN1MAPTKMT2AMMP3 | |
| SCHEMBL8123369 | 0.74 | PDCD1 (0.44) | DHODHGABRA1GABRB2S1PR1KMT2A | |
| SCHEMBL8632293 | 0.74 | KMT2A (0.46) | GABRA1GABRB2S1PR1MEN1POLB | |
| SCHEMBL6923032 | 0.73 | MAOB (0.43) | GABRA1GABRB2MEN1POLBMAPT | |
| SCHEMBL12074936 | 0.73 | KIF11 (0.42) | TNFPOLBMAPT | |
| SCHEMBL11257186 | 0.72 | PDE3B (0.40) | GABRA1GABRB2 | |
| SCHEMBL8244525 | 0.72 | ESR2 (0.54) | S1PR1PPARGALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163610-A2 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-29 | — | — | WO | disclosed |