Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | RPA1 | P27694 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990205 | 0.94 | RXRA (0.46) | RXRARXRBRXRGTP53MALT1 | |
| SCHEMBL9989687 | 0.90 | MALT1 (0.50) | RXRARXRBRXRGTP53MALT1 | |
| SCHEMBL9989284 | 0.90 | TP53 (0.51) | RXRARXRBRXRGTP53MALT1 | |
| SCHEMBL9988550 | 0.88 | TP53 (0.47) | RXRARXRBRXRGTP53MALT1 | |
| SCHEMBL9989283 | 0.88 | TP53 (0.45) | RXRARXRBRXRGTP53MALT1 | |
| SCHEMBL9989639 | 0.87 | ALOX5 (0.55) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9988542 | 0.86 | ALDH1A1 (0.49) | RXRARXRBRXRGTP53MALT1 | |
| SCHEMBL9988474 | 0.86 | RXRA (0.51) | RXRARXRBRXRGTP53MALT1 | |
| SCHEMBL9990241 | 0.85 | TP53 (0.45) | RXRARXRBRXRGTP53MALT1 | |
| SCHEMBL9989048 | 0.85 | RXRA (0.49) | RXRARXRBRXRGTP53MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |