Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15025792 | 0.90 | SLC22A12 (0.39) | SLC22A12 | |
| SCHEMBL9994630 | 0.84 | DGAT1 (0.39) | SLC22A12 | |
| SCHEMBL12069098 | 0.82 | SLC22A12 (0.51) | SLC22A12 | |
| SCHEMBL9994221 | 0.73 | SLC22A12 (0.74) | SLC22A12 | |
| SCHEMBL12069059 | 0.72 | SLC22A12 (0.67) | SLC22A12 | |
| SCHEMBL12069096 | 0.71 | SLC22A12 (0.68) | SLC22A12 | |
| SCHEMBL9994029 | 0.70 | SLC22A12 (0.69) | SLC22A12 | |
| SCHEMBL20924043 | 0.70 | NOTUM (0.46) | — | |
| SCHEMBL12071326 | 0.68 | SLC22A12 (0.70) | SLC22A12 | |
| SCHEMBL12069320 | 0.68 | SLC22A12 (0.54) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212135-B2 | Phenylthioacetate compounds, compositions and methods of use | ARDEA BIOSCIENCES, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150322006-A1 | PHENYLTHIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES, INC. | 2015-11-12 | — | — | US | disclosed |
| US-20130150381-A1 | PHENYLTHIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCE, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| EP-2582664-A2 | PHENYLTHIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Ardea Biosciences, Inc. (US) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159840-A2 | PHENYLTHIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | ARDEA BIOSCIENCES, INC. (US) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150381-A1 | PHENYLTHIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | MPST, PON1, NUDT1 | SLC22A12 628/4885 |
| US-20150322006-A1 | PHENYLTHIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | PON1, NUDT1, HPRT1 | SLC22A12 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.