Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271206 | 0.79 | MGLL (0.48) | MGLLL3MBTL1ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL5505931 | 0.79 | MGLL (0.46) | MGLLL3MBTL1NAAAADAMTS4ADAMTS5 | |
| SCHEMBL1864733 | 0.79 | MGLL (0.44) | MGLLL3MBTL1NAAAADAMTS4ADAMTS5 | |
| SCHEMBL1864730 | 0.79 | MGLL (0.44) | MGLLL3MBTL1NAAAADAMTS4ADAMTS5 | |
| SCHEMBL31715409 | 0.74 | ALDH1A1 (0.57) | MGLLL3MBTL1ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL5511617 | 0.73 | MGLL (0.53) | MGLLL3MBTL1NAAAADAMTS4ADAMTS5 | |
| SCHEMBL9996323 | 0.73 | MGLL (0.44) | MGLLL3MBTL1ADAMTS4ADAMTS5ALDH1A1 | |
| SCHEMBL13503017 | 0.73 | KMT2A (0.44) | MGLLL3MBTL1NAAAADAMTS4ADAMTS5 | |
| SCHEMBL4971085 | 0.72 | L3MBTL1 (0.41) | MGLLL3MBTL1NAAAADAMTS4ADAMTS5 | |
| SCHEMBL4971079 | 0.72 | L3MBTL1 (0.41) | MGLLL3MBTL1NAAAADAMTS4ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-B1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2011-12-21 | — | — | EP | disclosed |