Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971079 | 1.00 | L3MBTL1 (0.41) | L3MBTL1MGLLGAANAAANPY5R | |
| SCHEMBL3617574 | 0.77 | NAAA (0.45) | L3MBTL1MGLLGAANAAAKMT2A | |
| SCHEMBL1864733 | 0.77 | MGLL (0.44) | L3MBTL1MGLLGAANAAAKMT2A | |
| SCHEMBL1864730 | 0.77 | MGLL (0.44) | L3MBTL1MGLLGAANAAAKMT2A | |
| SCHEMBL2993617 | 0.76 | L3MBTL1 (0.41) | L3MBTL1GAANAAAKMT2AMEN1 | |
| SCHEMBL7329621 | 0.73 | GAA (0.52) | MGLLGAASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3404977 | 0.73 | MGLL (0.51) | MGLLGAAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL13503017 | 0.73 | KMT2A (0.44) | L3MBTL1MGLLGAANAAAKMT2A | |
| SCHEMBL9996320 | 0.72 | MGLL (0.43) | L3MBTL1MGLLGAANAAAKMT2A | |
| SCHEMBL13256223 | 0.71 | MGLL (0.49) | L3MBTL1MGLLGAANAAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-A1 | ASPARTIC PROTEASE INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070201-A1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |