Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9997528 | 0.87 | KMT2A (0.48) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL9997385 | 0.82 | POLB (0.41) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL9996879 | 0.80 | KMT2A (0.41) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL9997302 | 0.74 | KAT6A (0.42) | KDM4EMAPT | |
| SCHEMBL9997179 | 0.70 | PTK2B (0.34) | LMNASMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL15880603 | 0.67 | CA1 (0.73) | CA12CA9LMNASMN1; SMN2HTT | |
| SCHEMBL6927327 | 0.66 | LMNA (0.69) | CA12CA9LMNASMN1; SMN2HTT | |
| SCHEMBL9997441 | 0.66 | FBP1 (0.39) | — | |
| SCHEMBL4608475 | 0.65 | LMNA (0.67) | CA12CA9LMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL4609744 | 0.64 | LMNA (0.65) | CA12CA9LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |