Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996879 | 0.83 | KMT2A (0.41) | ALDH1A1GFERMEN1KMT2ALMNA | |
| SCHEMBL9997382 | 0.82 | CA12 (0.44) | POLBALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9997010 | 0.80 | EDNRB (0.37) | ALDH1A1GFERKMT2ALMNASMN1; SMN2 | |
| SCHEMBL9997338 | 0.78 | MEP1B (0.47) | POLBALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9997302 | 0.77 | KAT6A (0.42) | — | |
| SCHEMBL9997179 | 0.72 | PTK2B (0.34) | POLBL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9997441 | 0.68 | FBP1 (0.39) | — | |
| SCHEMBL21857831 | 0.66 | GAA (0.48) | POLBALDH1A1MEN1KMT2AGAA | |
| SCHEMBL10702820 | 0.65 | — | — | |
| SCHEMBL1993413 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |