Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998826 | 0.95 | MEN1 (0.52) | MAPTKMT2A | |
| SCHEMBL4498016 | 0.95 | MEN1 (0.52) | MAPTKMT2A | |
| SCHEMBL4721901 | 0.82 | KMT2A (0.49) | MAPTKMT2ANPSR1 | |
| SCHEMBL4724944 | 0.78 | KMT2A (0.52) | MAPTKMT2ANPSR1 | |
| SCHEMBL4765488 | 0.78 | KMT2A (0.52) | MAPTKMT2ANPSR1 | |
| SCHEMBL9998442 | 0.77 | NR4A2 (0.54) | — | |
| SCHEMBL9998326 | 0.76 | KDM4E (0.48) | — | |
| SCHEMBL4763232 | 0.71 | P2RX3 (0.62) | — | |
| SCHEMBL978395 | 0.69 | KMT2A (0.75) | MAPTKMT2ANPSR1 | |
| SCHEMBL9998699 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917262-B1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AS P2X3 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2011-12-14 | — | — | EP | disclosed |