Ornithine

Ornithine

SCHEMBL9998924

CC(C)(C)OC(=O)c1c[nH]c(CN)n1.NCCC[C@H](N)C(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.38
SLC7A5 Q01650 2/20 0.37
CPB2 Q96IY4 5/20 0.36
CPB1 P15086 2/20 0.32
CYP3A4 P08684 1/20 0.30
ARG1 P05089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3794190 0.84 GABRA1 (0.35)
Ornithine SCHEMBL3801714 0.74 GSR (0.39) GSRSLC7A5CPB2CPB1ARG1
Ornithine SCHEMBL9998922 0.69 MEN1 (0.38) GSR
SCHEMBL4636005 0.66 GABRA1 (0.37)
Ornithine SCHEMBL3443860 0.65 GSR (0.78) GSRCYP3A4ARG1
Ornithine Aketoglutarate SCHEMBL28452040 0.65 GSR (0.78) GSRCYP3A4ARG1
Ornithine Aketoglutarate SCHEMBL28086774 0.65 GSR (0.78) GSRCPB2ARG1
Ornithine SCHEMBL624782 0.65 GSR (0.86) GSRCPB2ARG1
D-Ornithine SCHEMBL43724 0.65
D-Ornithine SCHEMBL1537220 0.65 GSR (0.86) GSRCPB2ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110312877-A1 ENGINEERED TUNABLE NANOPARTICLES FOR DELIVERY OF THERAPEUTICS, DIAGNOSTICS, AND EXPERIMENTAL COMPOUNDS AND RELATED COMPOSITIONS FOR THERAPEUTIC USE APARNA BIOSCEIENCES (US) 2011-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110312877-A1 ENGINEERED TUNABLE NANOPARTICLES FOR DELIVERY OF THERAPEUTICS, DIAGNOSTICS, AND EXPERIMENTAL COMPOUNDS AND RELATED COMPOSITIONS FOR THERAPEUTIC USE TLR3, CHIA, TSG101 GSR 2747/4885SLC7A5 3132/4885CPB2 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.