SCHEMBL9999377

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL218655	0.88	ELANE (0.56)	ELANECYP3A4KMT2AMEN1LMNA
	SCHEMBL14173262	0.83	ELANE (0.51)	ELANECYP3A4KMT2AMEN1LMNA
	SCHEMBL26846471	0.83	LMNA (0.59)	ELANECYP3A4KMT2AMEN1LMNA
	SCHEMBL13524175	0.83	CYP3A4 (0.65)	ELANECYP3A4KMT2AMEN1LMNA
	SCHEMBL1437007	0.83	ELANE (0.56)	ELANECYP3A4KMT2AMEN1LMNA
	SCHEMBL31097939	0.81	CYP3A4 (0.68)	ELANECYP3A4KMT2AMEN1LMNA
	SCHEMBL220625	0.81	CYP3A4 (0.68)	ELANECYP3A4KMT2AMEN1LMNA
	SCHEMBL7186457	0.81	CES2 (0.50)	ELANECYP3A4KMT2AMEN1LMNA
	SCHEMBL28992157	0.81	ELANE (0.46)	ELANECYP3A4KMT2AMEN1LMNA
	SCHEMBL29584051	0.81	ELANE (0.46)	ELANECYP3A4KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.