SCHEMBL9999808

SCHEMBL9999808

Cc1ccc(N(c2ccc(C)cc2)c2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.51
FFAR1 O14842 1/20 0.44
CDK1 P06493 1/20 0.44
CCNB1 P14635 1/20 0.44
CCNA2 P20248 1/20 0.44
CDK2 P24941 1/20 0.44
CDK7 P50613 1/20 0.44
CCNH P51946 1/20 0.44
CCNA1 P78396 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
MAPT P10636 4/20 0.43
GAA P10253 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
RORC P51449 4/20 0.43
MGLL Q99685 1/20 0.42
RAPGEF4 Q8WZA2 1/20 0.41
HTT P42858 2/20 0.41
ALDH1A1 P00352 1/20 0.41
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8585252 0.95 NFE2L2 (0.47) NFE2L2FFAR1CDK1CCNB1CCNA2
SCHEMBL14416254 0.87 ALDH1A1 (0.50) MAPTTDP1MGLLHTTALDH1A1
SCHEMBL8583893 0.87 CETP (0.46) NFE2L2MAPTRORCMGLLRAPGEF4
SCHEMBL7592350 0.87 TSHR (0.52) NFE2L2MAPTGAATDP1MGLL
SCHEMBL12937148 0.85 MGLL (0.44) MAPTRORCMGLLALDH1A1TSHR
SCHEMBL6290803 0.85 ALDH1A1 (0.52) MAPTTDP1MGLLHTTALDH1A1
SCHEMBL9617277 0.84 NFE2L2 (0.41) NFE2L2FFAR1CDK1CCNB1CCNA2
SCHEMBL21391889 0.84 TSHR (0.45) NFE2L2MAPTTDP1ALDH1A1TSHR
SCHEMBL9999806 0.83 NFE2L2 (0.40) NFE2L2FFAR1CDK1CCNB1CCNA2
SCHEMBL16386576 0.83 CETP (0.43) NFE2L2MAPTRORCHTTCETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124248-B2 Light-emissive polymer blends and light-emissive devices made from the same CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-02-28 US disclosed
US-20070154736-A1 Light-Emissive Polymer Blends and Light-Emissive Devices Made From the Same CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2007-07-05 US disclosed