SCHEMBL5199097

SCHEMBL5199097

O=C1NN(c2ccccc2)C(=O)C1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.58
MEN1 O00255 6/20 0.58
MAPT P10636 5/20 0.50
ALDH1A1 P00352 3/20 0.50
POLB P06746 2/20 0.50
SRC P12931 2/20 0.46
ABL1 P00519 1/20 0.46
GAA P10253 8/20 0.45
LMNA P02545 3/20 0.45
NPC1 O15118 1/20 0.45
PKM P14618 1/20 0.45
DOCK2 Q92608 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
ALOX12 P18054 1/20 0.44
HPGD P15428 2/20 0.43
GRK5 P34947 1/20 0.41
TYRO3 Q06418 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13977390 0.79 KMT2A (0.54) KMT2AMEN1MAPTALDH1A1POLB
SCHEMBL3762404 0.69 MEN1 (0.44) KMT2AMEN1MAPTALDH1A1POLB
SCHEMBL3762408 0.69 MEN1 (0.44) KMT2AMEN1MAPTALDH1A1POLB
SCHEMBL3762412 0.69 MEN1 (0.44) KMT2AMEN1MAPTALDH1A1POLB
SCHEMBL3043229 0.68 GAA (0.64) KMT2AMEN1MAPTALDH1A1POLB
SCHEMBL3755954 0.67 ITGA4 (0.65) KMT2AMEN1MAPTALDH1A1POLB
SCHEMBL11210741 0.65 GAA (0.45) KMT2AMEN1MAPTALDH1A1POLB
SCHEMBL29509542 0.65 GAA (0.41) KMT2AMEN1MAPTALDH1A1POLB
SCHEMBL6735952 0.64 NPC1 (0.40) KMT2AMEN1MAPTALDH1A1GAA
SCHEMBL10603833 0.63 ALOX5 (0.53) KMT2AMEN1MAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1291006-B1 HAIR BLEACH OR HAIR DYE KAO CORP (JP) 2007-08-15 EP disclosed
US-7147668-B2 Hair bleach KAO CORPORATION (JP) 2006-12-12 US disclosed
EP-0779536-B1 Light-and heat-sensitive recording material and recording method by use thereof KONISHIROKU PHOTO IND (JP) 2005-10-19 EP disclosed
US-20030192133-A1 Hair bleach or hair dye KAO CORPORATION (JP) 2003-10-16 US disclosed
EP-1291006-A1 HAIR BLEACH OR HAIR DYE Kao Corporation (JP) 2003-03-12 EP disclosed
US-5789135-A Light-and heat-sensitive recording material and recording method by use thereof KONICA CORPORATION (JP) 1998-08-04 US disclosed
EP-0779536-A1 Light-and heat-sensitive recording material and recording method by use thereof KONICA CORPORATION (JP) 1997-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030192133-A1 Hair bleach or hair dye LPO, GPX4, POLL KMT2A 3688/4885MEN1 2912/4885MAPT 1311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.