Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOCK2 | Q92608 | 1/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 10/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977765 | 1.00 | DOCK2 (1.00) | DOCK2DYRK1AKMT2AMEN1JAK2 | |
| SCHEMBL13977382 | 0.82 | DOCK2 (0.69) | DOCK2DYRK1AKMT2AMEN1JAK2 | |
| SCHEMBL13977767 | 0.75 | DOCK2 (0.60) | DOCK2DYRK1AKMT2AMEN1JAK2 | |
| SCHEMBL14712961 | 0.75 | DOCK2 (0.60) | DOCK2DYRK1AKMT2AMEN1MAPT | |
| SCHEMBL14712901 | 0.73 | METAP1 (0.61) | DOCK2KMT2AMEN1MAPTPOLB | |
| SCHEMBL10026592 | 0.69 | DOCK2 (0.53) | DOCK2DYRK1AKMT2AMEN1MAPT | |
| SCHEMBL5736034 | 0.65 | MEN1 (0.79) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL5736031 | 0.65 | MEN1 (0.79) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL11461138 | 0.65 | ALDH1A1 (0.56) | DOCK2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL5199097 | 0.64 | KMT2A (0.58) | DOCK2KMT2AMEN1JAK2ZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119424418-A | Application of DOCK2 inhibitor CPYPP in preparation of antithrombotic drugs | 华中科技大学 | 2025-02-14 | — | — | CN | claimed |
| CN-117281791-A | Targeting drug delivery nano microsphere based on immune cell membrane and preparation method and application thereof | 中山大学附属第八医院(深圳福田) | 2023-12-26 | — | — | CN | claimed |
| US-20220290183-A1 | METHOD FOR INTRACELLULAR DELIVERY OF COMPOUNDS USING CELL FORCE AND SHAPE WITH ELECTRIC FIELDS | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2022-09-15 | — | — | US | claimed |
| US-11311523-B2 | Pyridinone compound and use thereof | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2022-04-26 | — | — | US | claimed |
| CN-119424418-A | Application of DOCK2 inhibitor CPYPP in preparation of antithrombotic drugs | 华中科技大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-119424418-A | Application of DOCK2 inhibitor CPYPP in preparation of antithrombotic drugs | 华中科技大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-117281791-A | Targeting drug delivery nano microsphere based on immune cell membrane and preparation method and application thereof | 中山大学附属第八医院(深圳福田) | 2023-12-26 | — | — | CN | disclosed |
| CN-117281791-A | Targeting drug delivery nano microsphere based on immune cell membrane and preparation method and application thereof | 中山大学附属第八医院(深圳福田) | 2023-12-26 | — | — | CN | disclosed |
| WO-2023089850-A1 | BIOMARKER FOR DIAGNOSIS OF COVID-19, SCREENING METHOD FOR DRUGS TO TREAT OR PREVENT COVID-19 FROM BECOMING SEVERE, METHOD FOR TREATING COVID-19, AND METHOD FOR PREVENTING COVID-19 FROM BECOMING SEVERE | 慶應義塾 | 2023-05-25 | — | — | WO | disclosed |
| US-20220290183-A1 | METHOD FOR INTRACELLULAR DELIVERY OF COMPOUNDS USING CELL FORCE AND SHAPE WITH ELECTRIC FIELDS | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2022-09-15 | — | — | US | disclosed |
| US-11311523-B2 | Pyridinone compound and use thereof | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2022-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11311523-B2 | Pyridinone compound and use thereof | DOCK5, DOCK2, CIB1 | DOCK2 2/4885DYRK1A 2775/4885KMT2A 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.