SCHEMBL29627161

SCHEMBL29627161

O=C1NN(c2ccccc2)C(=O)/C1=C/C=C/c1ccccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DOCK2 Q92608 1/20 1.00
DYRK1A Q13627 2/20 0.55
KMT2A Q03164 11/20 0.52
MEN1 O00255 10/20 0.52
JAK2 O60674 2/20 0.50
ZAP70 P43403 2/20 0.50
SYK P43405 1/20 0.50
MAPT P10636 8/20 0.48
POLB P06746 7/20 0.48
ALDH1A1 P00352 6/20 0.48
KDM4E B2RXH2 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
SRC P12931 2/20 0.47
GAA P10253 3/20 0.44
HPGD P15428 1/20 0.44
LMNA P02545 2/20 0.44
PKM P14618 2/20 0.44
MAPK1 P28482 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
ABL1 P00519 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13977765 1.00 DOCK2 (1.00) DOCK2DYRK1AKMT2AMEN1JAK2
SCHEMBL13977382 0.82 DOCK2 (0.69) DOCK2DYRK1AKMT2AMEN1JAK2
SCHEMBL13977767 0.75 DOCK2 (0.60) DOCK2DYRK1AKMT2AMEN1JAK2
SCHEMBL14712961 0.75 DOCK2 (0.60) DOCK2DYRK1AKMT2AMEN1MAPT
SCHEMBL14712901 0.73 METAP1 (0.61) DOCK2KMT2AMEN1MAPTPOLB
SCHEMBL10026592 0.69 DOCK2 (0.53) DOCK2DYRK1AKMT2AMEN1MAPT
SCHEMBL5736034 0.65 MEN1 (0.79) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL5736031 0.65 MEN1 (0.79) KMT2AMEN1MAPTPOLBALDH1A1
SCHEMBL11461138 0.65 ALDH1A1 (0.56) DOCK2KMT2AMEN1MAPTALDH1A1
SCHEMBL5199097 0.64 KMT2A (0.58) DOCK2KMT2AMEN1JAK2ZAP70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119424418-A Application of DOCK2 inhibitor CPYPP in preparation of antithrombotic drugs 华中科技大学 2025-02-14 CN claimed
CN-117281791-A Targeting drug delivery nano microsphere based on immune cell membrane and preparation method and application thereof 中山大学附属第八医院(深圳福田) 2023-12-26 CN claimed
US-20220290183-A1 METHOD FOR INTRACELLULAR DELIVERY OF COMPOUNDS USING CELL FORCE AND SHAPE WITH ELECTRIC FIELDS VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2022-09-15 US claimed
US-11311523-B2 Pyridinone compound and use thereof KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2022-04-26 US claimed
CN-119424418-A Application of DOCK2 inhibitor CPYPP in preparation of antithrombotic drugs 华中科技大学 2025-02-14 CN disclosed
CN-119424418-A Application of DOCK2 inhibitor CPYPP in preparation of antithrombotic drugs 华中科技大学 2025-02-14 CN disclosed
CN-117281791-A Targeting drug delivery nano microsphere based on immune cell membrane and preparation method and application thereof 中山大学附属第八医院(深圳福田) 2023-12-26 CN disclosed
CN-117281791-A Targeting drug delivery nano microsphere based on immune cell membrane and preparation method and application thereof 中山大学附属第八医院(深圳福田) 2023-12-26 CN disclosed
WO-2023089850-A1 BIOMARKER FOR DIAGNOSIS OF COVID-19, SCREENING METHOD FOR DRUGS TO TREAT OR PREVENT COVID-19 FROM BECOMING SEVERE, METHOD FOR TREATING COVID-19, AND METHOD FOR PREVENTING COVID-19 FROM BECOMING SEVERE 慶應義塾 2023-05-25 WO disclosed
US-20220290183-A1 METHOD FOR INTRACELLULAR DELIVERY OF COMPOUNDS USING CELL FORCE AND SHAPE WITH ELECTRIC FIELDS VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2022-09-15 US disclosed
US-11311523-B2 Pyridinone compound and use thereof KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2022-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11311523-B2 Pyridinone compound and use thereof DOCK5, DOCK2, CIB1 DOCK2 2/4885DYRK1A 2775/4885KMT2A 3024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.