SCHEMBL26622682

SCHEMBL26622682

Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](COCc3ccccc3)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.62
NT5E P21589 2/20 0.58
FUT6 P51993 4/20 0.58
KRAS P01116 2/20 0.57
FUT5 Q11128 1/20 0.56
P2RY2 P41231 1/20 0.56
P2RY4 P51582 1/20 0.56
P2RY6 Q15077 1/20 0.56
HINT1 P49773 1/20 0.55
GPR17 Q13304 2/20 0.54
TAS1R3 Q7RTX0 1/20 0.53
TAS1R1 Q7RTX1 1/20 0.53
IMPDH2 P12268 1/20 0.52
DCPS Q96C86 1/20 0.52
P2RX3 P56373 1/20 0.51
POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26622675 0.94 NT5E (0.61) TGM2NT5EFUT6KRASFUT5
SCHEMBL26622655 0.89 TGM2 (0.66) TGM2NT5EKRASFUT5P2RY2
SCHEMBL26208040 0.87 NT5E (0.58) TGM2NT5EFUT6KRASP2RY2
SCHEMBL26622717 0.87 TGM2 (0.65) TGM2NT5EKRASFUT5P2RY2
SCHEMBL26207486 0.87 TGM2 (0.65) TGM2NT5EKRASFUT5P2RY2
SCHEMBL26622665 0.87 TGM2 (0.68) TGM2NT5EKRASFUT5P2RY2
SCHEMBL26622787 0.87 TGM2 (0.70) TGM2NT5EKRASFUT5P2RY2
SCHEMBL26622676 0.87 HINT1 (0.62) TGM2NT5EHINT1
SCHEMBL26209516 0.87 TGM2 (0.66) TGM2NT5EKRASFUT5P2RY2
SCHEMBL26624153 0.87 TGM2 (0.66) TGM2NT5EKRASFUT5P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 TGM2 2548/4885NT5E 803/4885FUT6 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.