MMP24

Matrix metalloproteinase-24 · Q9Y5R2 · MMP24 on Sugi Atlas →

246 patent compounds predicted against MMP24, 197 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Marimastat Marimastat (SCHEMBL34033) 1.00 1/20
Marimastat Marimastat (SCHEMBL134999) 1.00 1/20
Marimastat Marimastat (SCHEMBL1821430) 1.00 1/20
Marimastat Marimastat (SCHEMBL8189167) 1.00 1/20
Marimastat Marimastat (SCHEMBL8193003) 1.00 1/20
Marimastat Marimastat (SCHEMBL13253251) 1.00 1/20
Marimastat Marimastat (SCHEMBL13575773) 1.00 1/20
Marimastat Marimastat (SCHEMBL17799241) 1.00 1/20
Marimastat Marimastat (SCHEMBL20793036) 1.00 1/20
Marimastat Marimastat (SCHEMBL31231856) 1.00 1/20
Marimastat Marimastat (SCHEMBL7931107) 0.97 1/20
Marimastat Marimastat (SCHEMBL7933374) 0.97 1/20
SCHEMBL7983019 SCHEMBL7983019 0.78 1/20
SCHEMBL19286781 SCHEMBL19286781 0.78 1/20
SCHEMBL8026827 SCHEMBL8026827 0.77 1/20
SCHEMBL9714151 SCHEMBL9714151 0.77 1/20
SCHEMBL17128737 SCHEMBL17128737 0.77 1/20
SCHEMBL1847104 SCHEMBL1847104 0.75 1/20
SCHEMBL6435806 SCHEMBL6435806 0.75 1/20
SCHEMBL9714274 SCHEMBL9714274 0.75 1/20

Clinical trials — most relevant to MMP24 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY PHASE4SUSPENDED
Doxycycline In Lymphangioleiomyomatosis (LAM) PHASE4COMPLETED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast PHASE2COMPLETED
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma PHASE2UNKNOWN
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer PHASE1COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement PHASE1COMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects nanAVAILABLE
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar nanCOMPLETED
Influence of Statins in Artery Aneurysms nanUNKNOWN
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial nanCOMPLETED
Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia nanUNKNOWN
Prognostic Indices of Atheromatosis Severity and Coronary Artery Bypass Surgery Outcomes for Patients With Coronary Artery Disease nanACTIVE_NOT_RECRUITING
Apoptotic Changes in Gingiva Caused by Smoking nanCOMPLETED
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction nanCOMPLETED
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation nanCOMPLETED
Periodontal Health in Post COVID-19 Patients nanUNKNOWN
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma nanUNKNOWN
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma nanCOMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development nanCOMPLETED
High-Dose Vitamin D3 for Diabetic Foot Ulcer Healing: Randomized Controlled Trial nanCOMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence nanWITHDRAWN
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels nanCOMPLETED
Plasma and Scarring of Diabetic Ulcers nanCOMPLETED
Matrix Metalloproteinase (MMP) in Heart Failure nanCOMPLETED
Salivary Markers in Periodontal Disorders nanCOMPLETED
Matrix Metalloproteinases and Human Papillomavirus in Dysplasias and Cancers of the Cervix nanCOMPLETED
Matrix Metalloproteinases 7 and 9 in Rheumatoid Arthritis Patients With Interstitial Lung Disease nanNOT_YET_RECRUITING
Interest of Dosage of Anti-PB230, Anti-PB180 and Cytokines for Monitoring of Patients Suffering From Bullous Pemphigoid nanCOMPLETED
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS nanCOMPLETED
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MMP24 binder may also engage these)

ProteinNameSimilarity
Q95220 1.000 Q95220 →
MMP14 Matrix metalloproteinase-14 1.000 landscape →
P53690 1.000 P53690 →
Q9R0S2 1.000 Q9R0S2 →
Q99PW6 1.000 Q99PW6 →
Q10739 1.000 Q10739 →
O54732 1.000 O54732 →
Q3U435 0.998 Q3U435 →
MMP15 Matrix metalloproteinase-15 0.998 landscape →
Q9GLE4 0.998 Q9GLE4 →
Q5RES1 0.998 Q5RES1 →
Q9WTR0 0.996 Q9WTR0 →
Q9XT90 0.995 Q9XT90 →
P41245 0.995 P41245 →
P57748 0.993 P57748 →
P52176 0.993 P52176 →
MMP9 Matrix metalloproteinase-9 0.992 landscape →
O18767 0.992 O18767 →
Q11005 0.991 Q11005 →
O55123 0.991 O55123 →
O35548 0.991 O35548 →
P50757 0.991 P50757 →
Q499S5 0.991 Q499S5 →
MMP16 Matrix metalloproteinase-16 0.990 landscape →
Q9GLE5 0.990 Q9GLE5 →
P41246 0.989 P41246 →
MMP20 Matrix metalloproteinase-20 0.989 landscape →
P07152 0.989 P07152 →
MMP3 Stromelysin-1 0.989 landscape →
LOXL3 Lysyl oxidase homolog 3 0.989 landscape →