SCHEMBL1278875

SCHEMBL1278875

CC(C)=NNC(=O)c1cc2ccccc2cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR39 O43194 1/20 0.67
MEN1 O00255 8/20 0.65
KMT2A Q03164 8/20 0.65
MAPT P10636 7/20 0.65
POLB P06746 6/20 0.65
GAA P10253 6/20 0.65
KDM4E B2RXH2 5/20 0.65
RAB9A P51151 4/20 0.65
RECQL P46063 4/20 0.65
THRB P10828 4/20 0.65
NPC1 O15118 3/20 0.65
USP2 O75604 3/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
PLA2G1B P04054 1/20 0.65
ALOX12 P18054 1/20 0.65
BLM P54132 1/20 0.65
MCL1 Q07820 1/20 0.65
ESR2 Q92731 1/20 0.65
ATG4B Q9Y4P1 1/20 0.65
HSP90AA1 P07900 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29587172 1.00 GPR39 (0.67) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL30240764 0.85 GPR39 (0.81) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL1278646 0.85 MEN1 (0.66) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL30240801 0.85 MEN1 (0.66) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL5149471 0.85 GPR39 (0.81) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL1278645 0.85 MEN1 (0.66) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL6634348 0.85 GPR39 (0.81) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL5149465 0.85 GPR39 (0.81) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL6634707 0.85 MEN1 (0.66) GPR39MEN1KMT2AMAPTPOLB
SCHEMBL2278849 0.83 GAA (0.71) GPR39MEN1KMT2AMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 EP claimed
WO-2023199974-A1 RUBBER COMPOSITION 大塚化学株式会社 2023-10-19 WO claimed
EP-2954001-B1 TYRE HIGH-STIFFNESS COMPOUND BRIDGESTONE CORP (JP) 2017-01-04 EP claimed
US-20150368445-A1 TYRE HIGH-STIFFNESS COMPOUND BRIDGESTONE CORPORATION (JP) 2015-12-24 US claimed
EP-1184412-B1 Rubber composition and heavy duty pneumetic tire using the rubber composition BRIDGESTONE CORP (JP) 2005-01-12 EP claimed
EP-0909788-B1 RUBBER COMPOSITION AND PNEUMATIC TIRES BRIDGESTONE CORP (JP) 2004-12-01 EP claimed
US-6822027-B2 MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. BRIDGESTONE CORPORATION (JP) 2004-11-23 US claimed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US claimed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP claimed
US-20250257197-A1 RUBBER COMPOSITION OTSUKA CHEMICAL CO., LTD. (JP) 2025-08-14 US disclosed
WO-2025100279-A1 SIDEWALL RUBBER COMPOSITION AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
EP-4509558-A1 RUBBER COMPOSITION Otsuka Chemical Co., Ltd. (JP) 2025-02-19 EP disclosed
EP-4169736-B1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORP (JP) 2024-11-27 EP disclosed
US-20020077423-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION 2002-06-20 US disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 US disclosed
EP-1199331-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION (JP) 2002-04-24 EP disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 EP disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed