SCHEMBL38806

SCHEMBL38806

NNC(=O)c1ccc(Br)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OGG1 O15527 1/20 1.00
MPO P05164 2/20 0.64
CYP3A4 P08684 2/20 0.64
GFER P55789 2/20 0.64
KDM5A P29375 1/20 0.64
BLM P54132 1/20 0.64
PMP22 Q01453 1/20 0.64
HIF1A Q16665 1/20 0.64
KDM4E B2RXH2 6/20 0.61
ALDH1A1 P00352 4/20 0.61
MAPT P10636 3/20 0.61
LMNA P02545 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
GSK3B P49841 2/20 0.56
CYP1A2 P05177 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2A6 P11509 1/20 0.56
CYP2C19 P33261 1/20 0.56
CA1 P00915 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2678949 0.87 MPO (0.80) OGG1MPOCYP3A4GFERKDM5A
SCHEMBL343630 0.87 MPO (0.80) OGG1MPOCYP3A4GFERKDM5A
SCHEMBL9377797 0.87 OGG1 (0.75) OGG1MPOCYP3A4GFERKDM5A
SCHEMBL28188923 0.85 MPO (0.76) OGG1MPOCYP3A4GFERKDM5A
SCHEMBL12687823 0.83 OGG1 (0.71) OGG1MPOCYP3A4GFERKDM5A
SCHEMBL11134828 0.80 MPO (0.70) OGG1MPOCYP3A4GFERKDM5A
SCHEMBL752600 0.80 MPO (0.70) OGG1MPOCYP3A4GFERKDM5A
SCHEMBL1982518 0.80 POLB (0.68) OGG1GFERKDM4EALDH1A1MAPT
SCHEMBL8575405 0.80 OGG1 (0.67) OGG1GFERKDM4EALDH1A1MAPT
SCHEMBL13481186 0.80 POLB (0.68) OGG1GFERKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 718 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977832-A Benzoyl hydrazine antineoplastic compound and preparation method and application thereof 江苏海洋大学 2025-05-13 CN claimed
CN-119320349-A Quinoline acylhydrazone ligand, fe (II) spin cross complex thereof and synthesis method thereof 南京理工大学 2025-01-17 CN claimed
CN-117402125-A Preparation method of noo Bo Suan oxadiazole thioester compound, product and application thereof 南京林业大学 2024-01-16 CN claimed
US-11398630-B2 Method of generating energy from a hydrazide containing anode fuel, and fuel cell IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-07-26 US claimed
CN-113861149-A Fluorescent probe based on coumarin and p-bromobenzoyl hydrazine and preparation method thereof 齐鲁工业大学 2021-12-31 CN claimed
CN-113416266-A Aromatic hydrazide compound-cyclodextrin inclusion compound and preparation method thereof 湖北工业大学 2021-09-21 CN claimed
US-20210005900-A1 METHOD OF GENERATING ENERGY FROM A HYDRAZIDE CONTAINING ANODE FUEL, AND FUEL CELL IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-01-07 US claimed
US-10040741-B2 Method for manufacturing high purity glycol based compound SAMSUNG DISPLAY CO., LTD. (KR) 2018-08-07 US claimed
CN-108003178-A Acylhydrazone copper (II) complex and preparation method thereof and its application in urease activity is suppressed 辽宁师范大学 2018-05-08 CN claimed
US-20160297732-A1 METHOD FOR MANUFACTURING HIGH PURITY GLYCOL BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-13 US claimed
CN-105669491-A Acidylation method of amine 苏州大学 2016-06-15 CN claimed
CN-102659665-A Two compounds used as hole transport materials as well as production method and applications thereof NANJING UNIVERSITY OF TECHNOLOGY 2012-09-12 CN claimed
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-06-05 US claimed
WO-2002102301-A2 SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2002-12-27 WO claimed
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2002-09-12 US claimed
US-12509544-B2 Aqueous binder formulation BASF SE (DE) 2025-12-30 US disclosed
US-12325678-B2 Anti-fungals compounds targeting the synthesis of fungal sphingolipids THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-06-10 US disclosed
US-4309422-A INSECTICIDES VELSICOL CHEMICAL CORPORATION (US) 1982-01-05 US disclosed
US-4017540-A INSECTICIDES, MITICIDES THE UPJOHN COMPANY (US) 1977-04-12 US disclosed
US-3932661-A Anthelmintic methods employing benzoyl chloride phenylhydrazones THE UPJOHN COMPANY (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12325678-B2 Anti-fungals compounds targeting the synthesis of fungal sphingolipids ERG28, UGCG, SMPD1 OGG1 2842/4885MPO 2300/4885CYP3A4 3980/4885
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 OGG1 2317/4885MPO 2665/4885CYP3A4 1159/4885
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 OGG1 2317/4885MPO 2665/4885CYP3A4 1159/4885
US-12509544-B2 Aqueous binder formulation ADH1C, AKR1C1, AKR1C2 OGG1 2583/4885MPO 2515/4885CYP3A4 1529/4885
US-10040741-B2 Method for manufacturing high purity glycol based compound GK, GMDS, UGCG OGG1 1002/4885MPO 1470/4885CYP3A4 919/4885
US-20160297732-A1 METHOD FOR MANUFACTURING HIGH PURITY GLYCOL BASED COMPOUND GK, GMDS, UGCG OGG1 1002/4885MPO 1470/4885CYP3A4 919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.