Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 12/20 | 0.64 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237569 | 0.79 | TP53 (0.47) | TAS2R14 | |
| SCHEMBL31237571 | 0.78 | KMT2A (0.45) | TAS2R14MAPK8DYRK1A | |
| Flufenamic Acid SCHEMBL29356958 | 0.76 | RXFP1 (0.75) | TAS2R14MAPK8AURKAPTGS1PTGS2 | |
| Flufenamic Acid SCHEMBL17497 | 0.76 | RXFP1 (0.75) | TAS2R14MAPK8AURKAPTGS1PTGS2 | |
| SCHEMBL11330727 | 0.76 | TAS2R14 (0.82) | TAS2R14FABP4AKR1C3AKR1C2ADRA2B | |
| Flufenamic Acid SCHEMBL9845499 | 0.75 | RXFP1 (0.73) | TAS2R14MAPK8AURKAPTGS1PTGS2 | |
| Flufenamic Acid SCHEMBL11524554 | 0.75 | RXFP1 (0.73) | TAS2R14MAPK8AURKAPTGS1PTGS2 | |
| SCHEMBL29417535 | 0.75 | MAPT (0.51) | TAS2R14FABP4PTGS1PTGS2AKR1C3 | |
| SCHEMBL10186488 | 0.75 | FABP4 (0.71) | TAS2R14MAPK8AURKAFABP4PTGS1 | |
| SCHEMBL8708722 | 0.74 | SMARCA2 (0.72) | PIM1FLT3CDK9CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309726-B2 | Substituted piperazine compounds of formula 8 | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-11-13 | — | — | US | disclosed |
| EP-2150527-B1 | ANTHRANILIC ACID DERIVATIVE AS ANTICANCER AGENT AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2011-01-19 | — | — | EP | disclosed |
| US-20100016589-A1 | Novel Anthranilic Acid Derivative as Potential Anticancer Agent and a Process for the Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016589-A1 | Novel Anthranilic Acid Derivative as Potential Anticancer Agent and a Process for the Preparation Thereof | AADAC, API5, APEH | TAS2R14 3591/4885MAPK8 233/4885AURKA 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.