USP16 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL15817526	0.45	2/20
SCHEMBL11563775	0.44	2/20
SCHEMBL15817525	0.39	2/20
SCHEMBL4945778	0.46	1/20
SCHEMBL3070912	0.45	1/20
SCHEMBL4945586	0.45	1/20
SCHEMBL3130103	0.45	1/20
SCHEMBL13102294	0.44	1/20
SCHEMBL15818436	0.44	1/20
SCHEMBL4944811	0.43	1/20
SCHEMBL11121640	0.43	1/20
SCHEMBL6975177	0.43	1/20
SCHEMBL5418249	0.41	1/20
SCHEMBL7293717	0.41	1/20
SCHEMBL11475097	0.41	1/20

Clinical trials — most relevant to USP16 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients	PHASE4	NOT_YET_RECRUITING
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma	PHASE2	SUSPENDED
Relapsed and/or Refractory Non-Hodgkin Lymphoma Study	PHASE2	WITHDRAWN
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes	PHASE2	UNKNOWN
Extended Infusion Carfilzomib on a Weekly Schedule in Patients With Advanced Solid Tumors	PHASE1	COMPLETED
Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease	EARLY_PHASE1	RECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome	nan	RECRUITING
Clinical Trial of Levodopa/Carbidopa ( Sinemet) Therapy in Angel Man Syndrome	nan	COMPLETED
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
Study of Blood Samples From High-Risk Postmenopausal Women Who Received Treatment on Breast Cancer Prevention Clinical Trials NSABP-P-1 or NSABP-P-2	nan	UNKNOWN
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Relationship Between Nutritional State and Respiratory Muscle Weakness in Adult Patients With Bronchietasis	nan	UNKNOWN
The Significance of Urine UbA52 In the Diagnosis of Diabetic Nephropathy	nan	COMPLETED
Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis	nan	NOT_YET_RECRUITING
Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit	nan	COMPLETED
Prognostic Biomarkers in Tumor Tissue Samples From Young Patients With Neuroblastoma	nan	COMPLETED
Low Dose Melphalan and Bortezomib for AML and High-Risk MDS	nan	COMPLETED
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin	nan	UNKNOWN
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas	nan	RECRUITING
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract	nan	UNKNOWN
Evaluation of Proteasome as a Marker of Hepatocellular Carcinoma in Cirrhotic Patients Following Curative Treatment	nan	UNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Establishment of a Prospective Clinical-biological Database	nan	RECRUITING
Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer	nan	RECRUITING
The PREServation of MUScle Function in Critically Ill Patients (PRESMUS)	nan	UNKNOWN
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a USP16 binder may also engage these)

Protein	Name	Similarity
Q4R6X7	—	1.000	Q4R6X7 →
Q08DA3	—	1.000	Q08DA3 →
Q2KJ09	—	0.998	Q2KJ09 →
Q99LG0	—	0.998	Q99LG0 →
Q6PAW2	—	0.993	Q6PAW2 →
A8HAL1	—	0.993	A8HAL1 →
Q0VA64	—	0.989	Q0VA64 →
Q8R5K2	—	0.987	Q8R5K2 →
Q8K387	—	0.986	Q8K387 →
E9QG68	—	0.986	E9QG68 →
Q3KR59	—	0.985	Q3KR59 →
A5PMR2	—	0.984	A5PMR2 →
A6QNM7	—	0.984	A6QNM7 →
Q2NL57	—	0.984	Q2NL57 →
Q70EL2	—	0.984	Q70EL2 →
P52479	—	0.982	P52479 →
Q8TEY7	—	0.982	Q8TEY7 →
USP10	Ubiquitin carboxyl-terminal hydrolase 10	0.982	landscape →
Q6DIJ4	—	0.981	Q6DIJ4 →
Q28CN3	—	0.980	Q28CN3 →
Q5REG5	—	0.980	Q5REG5 →
Q91ZT5	—	0.979	Q91ZT5 →
B1AY15	—	0.978	B1AY15 →
A5PJS6	—	0.978	A5PJS6 →
A0JM59	—	0.978	A0JM59 →
Q7ZXR7	—	0.977	Q7ZXR7 →
O60934	—	0.976	O60934 →
Q8BW70	—	0.976	Q8BW70 →
Q9QXK2	—	0.976	Q9QXK2 →
Q8C2S0	—	0.976	Q8C2S0 →