Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.47 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350674 | 0.93 | PSEN1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2872778 | 0.91 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4160672 | 0.88 | MEN1 (0.56) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4725248 | 0.87 | SCARB1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4155967 | 0.83 | MAPT (0.59) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4161570 | 0.82 | KCNA3 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL351636 | 0.80 | FABP4 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2875809 | 0.80 | SCARB1 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19559314 | 0.79 | MAPT (0.61) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13696968 | 0.77 | PSEN1 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079999-B2 | Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings | ADVINCULA RIGOBERTO (US) | 2015-07-14 | — | — | US | disclosed |
| US-20090236229-A1 | METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2009-09-24 | — | — | US | disclosed |