SCHEMBL10001030

SCHEMBL10001030

Cc1ccc2c(c1)c1ccccc1c1nccnc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
HSP90AA1 P07900 1/20 0.47
MAOA P21397 1/20 0.44
CCR1 P32246 3/20 0.43
CCR8 P51685 3/20 0.43
CCR5 P51681 2/20 0.43
GABRP O00591 2/20 0.42
GABRD O14764 2/20 0.42
GABRA1 P14867 2/20 0.42
GABRB1 P18505 2/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRA5 P31644 2/20 0.42
GABRA3 P34903 2/20 0.42
GABRA2 P47869 2/20 0.42
GABRB2 P47870 2/20 0.42
GABRA4 P48169 2/20 0.42
GABRE P78334 2/20 0.42
GABRA6 Q16445 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20193202 0.96 NPC1 (0.47) NPC1L3MBTL1HSP90AA1MAOACCR1
SCHEMBL12346093 0.92 L3MBTL1 (0.57) NPC1L3MBTL1HSP90AA1MAOACCR1
SCHEMBL13330656 0.92 CCR1 (0.50) NPC1L3MBTL1HSP90AA1MAOACCR1
SCHEMBL10001027 0.90 NPC1 (0.50) NPC1L3MBTL1HSP90AA1MAOACCR1
SCHEMBL10001029 0.90 NPC1 (0.50) NPC1L3MBTL1HSP90AA1MAOACCR1
SCHEMBL17994960 0.90 NPC1 (0.50) NPC1L3MBTL1HSP90AA1MAOACCR1
SCHEMBL13330657 0.87 CCR1 (0.50) NPC1L3MBTL1HSP90AA1MAOACCR1
SCHEMBL19978073 0.86 NPC1 (0.50) NPC1L3MBTL1HSP90AA1MAOACCR1
SCHEMBL19003894 0.83 MAP4K4 (0.47) NPC1L3MBTL1HSP90AA1KMT2ABCHE
SCHEMBL17180585 0.82 KIF11 (0.54) NPC1MAOAKIF11MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021018270-A1 HOST COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 浙江华显光电科技有限公司 2021-02-04 WO disclosed
US-10243151-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-26 US disclosed
US-10038143-B2 Polymer compound, material for electronic elements, material for organic electroluminescent elements, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-07-31 US disclosed
US-20170250352-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-31 US disclosed
US-20170250352-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-31 US disclosed
US-9620723-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-11 US disclosed
US-9620723-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-11 US disclosed
US-20150249215-A1 POLYMER COMPOUND, MATERIAL FOR ELECTRONIC ELEMENTS, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 US disclosed
US-20150076470-A1 Luminescent Cyclometallated Iridium (III) Complexes Having Acetylide Ligands UNIV SOUTHERN CALIFORNIA (US) 2015-03-19 US disclosed
US-20150076470-A1 Luminescent Cyclometallated Iridium (III) Complexes Having Acetylide Ligands UNIV SOUTHERN CALIFORNIA (US) 2015-03-19 US disclosed
US-20130112961-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-05-09 US disclosed
US-20130112961-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-05-09 US disclosed
US-8343639-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-01 US disclosed
US-8343639-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-01 US disclosed
US-20120007061-A1 Luminescent Cyclometallated Iridium(III) Complexes Having Acetylide Ligands THE UNIVERSITY OF SOUTHERN CALIFORNIA 2012-01-12 US disclosed
US-20120007061-A1 Luminescent Cyclometallated Iridium(III) Complexes Having Acetylide Ligands THE UNIVERSITY OF SOUTHERN CALIFORNIA 2012-01-12 US disclosed
WO-2010027004-A1 ORGANIC SEMICONDUCTOR MATERIAL AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, LIGHTING SYSTEM, AND ELECTRONIC DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-03-11 WO disclosed
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-11 US disclosed
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-11 US disclosed
US-20100039024-A1 New Heterocyclic bridged biphenyls UDC IRELAND LIMITED (IE) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10243151-B2 Organic semiconductor material and light-emitting element, light-emitting device, lighting system, and electronic device using the same OXA1L, BECN1, MAP1LC3A NPC1 4299/4885L3MBTL1 2080/4885HSP90AA1 2722/4885
US-20170250352-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A NPC1 4299/4885L3MBTL1 2080/4885HSP90AA1 2722/4885
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A NPC1 4299/4885L3MBTL1 2080/4885HSP90AA1 2722/4885
US-20130112961-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A NPC1 4299/4885L3MBTL1 2080/4885HSP90AA1 2722/4885
US-20120007061-A1 Luminescent Cyclometallated Iridium(III) Complexes Having Acetylide Ligands ACACA, SIRT3, ICOSLG NPC1 4537/4885L3MBTL1 2663/4885HSP90AA1 3943/4885
US-20100039024-A1 New Heterocyclic bridged biphenyls BMP2, BPTF, PBDC1 NPC1 4466/4885L3MBTL1 3045/4885HSP90AA1 4108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.