Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29891596 | 0.82 | NOS1 (0.62) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL1202291 | 0.82 | NOS1 (0.62) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL1322626 | 0.73 | MAOA (0.52) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL10001734 | 0.71 | ALDH1A1 (0.53) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL13933160 | 0.71 | NPC1 (0.81) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL14644670 | 0.71 | ALDH1A1 (0.47) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL345690 | 0.70 | KIF11 (0.67) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL29362354 | 0.70 | KIF11 (0.67) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL9724162 | 0.68 | LMNA (0.67) | ALDH1A1NPC1MEN1KMT2APOLB | |
| SCHEMBL13412884 | 0.68 | MEN1 (0.65) | ALDH1A1NPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093258-B2 | Use of urokinase inhibitors for the treatment and/or prevention of neuropathological diseases | WILEX AG (DE) | 2012-01-10 | — | — | US | disclosed |
| US-8093258-B2 | Use of urokinase inhibitors for the treatment and/or prevention of neuropathological diseases | WILEX AG (DE) | 2012-01-10 | — | — | US | disclosed |
| US-20090069251-A1 | Use Of Urokinase Inhibitors for the Treatment and/or Prevention of Neuropathological Diseases | WILEX AG (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090069251-A1 | Use Of Urokinase Inhibitors for the Treatment and/or Prevention of Neuropathological Diseases | WILEX AG (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069251-A1 | Use Of Urokinase Inhibitors for the Treatment and/or Prevention of Neuropathological Diseases | PLAU, SERPINE1, PLAUR | ALDH1A1 2896/4885NPC1 2014/4885MEN1 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.