SCHEMBL10001921

SCHEMBL10001921

Cc1cc(=O)[nH]c2cc(NC(=O)CN(CCN3CCOCCN(CCN(COCO)CC(=O)O)CCOCC3)CC(=O)O)ccc12

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 8/20 0.48
▸ TNKS2 Q9H2K2 1/20 0.41
▸ LMNA P02545 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ CASR P41180 1/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10001935 0.99 TERT (0.47) TERTTNKS2LMNAALOX15TSHR
SCHEMBL10035654 0.93 TERT (0.55) TERTTNKS2LMNAALOX15TSHR
SCHEMBL10035653 0.92 TERT (0.54) TERTTNKS2LMNAALOX15TSHR
SCHEMBL10001931 0.88 TERT (0.51) TERTTNKS2LMNAALOX15TSHR
SCHEMBL10001934 0.84 TERT (0.49) TERTTNKS2ALOX15TSHRPOLB
SCHEMBL10035606 0.80 TERT (0.52) TERTTNKS2TSHRALDH1A1
SCHEMBL10001923 0.80 TERT (0.41) TERTTNKS2LMNAALOX15TSHR
SCHEMBL14367687 0.79 TERT (0.48) TERTLMNAKDM4EALDH1A1
SCHEMBL10001924 0.77 TERT (0.41) TERTTNKS2LMNAALOX15TSHR
SCHEMBL10035607 0.77 TERT (0.50) TERTTNKS2ALOX15TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110404-B2 Luminescent lanthanide binding chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-02-07 — — US disclosed
US-20080299675-A1 Luminescent Lanthanide Binding Chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2008-12-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299675-A1 Luminescent Lanthanide Binding Chelates HLCS, LYAR, SLC6A13 TERT 2908/4885TNKS2 3224/4885LMNA 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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