SCHEMBL10001924

SCHEMBL10001924

Cc1cc(NC(=O)CN(CCN2CCOCCN(CCN(CC(=O)O)CC(=O)NNC(=O)CCC3C(=O)C=CC3=O)CC2)CC(=O)O)cc2[nH]c(=O)ccc12

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 7/20 0.41
▸ TNKS2 Q9H2K2 1/20 0.36
▸ RAB9A P51151 1/20 0.35
▸ GBA1 P04062 1/20 0.34
▸ PAK1 Q13153 1/20 0.34
▸ TSHR P16473 1/20 0.33
▸ TNIK Q9UKE5 1/20 0.33
▸ CHRM3 P20309 1/20 0.33
▸ LMNA P02545 2/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10035653 0.84 TERT (0.54) TERTTNKS2RAB9APAK1TSHR
SCHEMBL10001934 0.83 TERT (0.49) TERTTNKS2RAB9APAK1TSHR
SCHEMBL10035654 0.83 TERT (0.55) TERTTNKS2RAB9ATSHRLMNA
SCHEMBL10001923 0.81 TERT (0.41) TERTTNKS2RAB9ATSHRTNIK
SCHEMBL10001931 0.80 TERT (0.51) TERTTNKS2RAB9APAK1TSHR
SCHEMBL14530618 0.79 TERT (0.39) TERTTNKS2RAB9APAK1TSHR
SCHEMBL10001936 0.78 TERT (0.39) TERTTNKS2RAB9ATSHRCHRM3
SCHEMBL10001935 0.78 TERT (0.47) TERTTNKS2PAK1TSHRTNIK
SCHEMBL10001921 0.77 TERT (0.48) TERTTNKS2TSHRLMNAALOX15
SCHEMBL10035607 0.77 TERT (0.50) TERTTNKS2RAB9APAK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110404-B2 Luminescent lanthanide binding chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-02-07 — — US disclosed
US-8110404-B2 Luminescent lanthanide binding chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-02-07 — — US disclosed
US-20080299675-A1 Luminescent Lanthanide Binding Chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2008-12-04 — — US disclosed
US-20080299675-A1 Luminescent Lanthanide Binding Chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2008-12-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299675-A1 Luminescent Lanthanide Binding Chelates HLCS, LYAR, SLC6A13 TERT 2908/4885TNKS2 3224/4885RAB9A 2317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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