SCHEMBL10001976

SCHEMBL10001976

Cc1cc(C)c(C)c(C(F)(F)F)c1C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16707367 0.83 PGK1 (0.31) PGK1PGK2
SCHEMBL28255936 0.83 ACHE (0.39)
Bromide SCHEMBL28807681 0.81 CYP3A4 (0.37)
SCHEMBL11406384 0.79 AR (0.41) PGK1PGK2
SCHEMBL9140039 0.78 PGK1 (0.31) PGK1PGK2
SCHEMBL24716330 0.78 CYP1A2 (0.35)
SCHEMBL10001971 0.77 AR (0.30)
SCHEMBL13816869 0.74 TRPA1 (0.35)
SCHEMBL11747128 0.74 SMN1; SMN2 (0.38) PGK1PGK2
SCHEMBL10993439 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402172-A Synthesis method of 3, 6-bis (trifluoromethyl) -pyromellitic dianhydride 中国科学院上海有机化学研究所 2024-01-16 CN claimed
CN-117402172-A Synthesis method of 3, 6-bis (trifluoromethyl) -pyromellitic dianhydride 中国科学院上海有机化学研究所 2024-01-16 CN disclosed
CN-117402172-A Synthesis method of 3, 6-bis (trifluoromethyl) -pyromellitic dianhydride 中国科学院上海有机化学研究所 2024-01-16 CN disclosed
CN-117384121-A Preparation method of 2,2' -di (trifluoromethyl) -4,4', 5' -biphenyl dianhydride 中国科学院上海有机化学研究所 2024-01-12 CN disclosed
US-11319410-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2022-05-03 US disclosed
US-11034797-B2 Polyimide precursor composition, use thereof and polyimide made therefrom ETERNAL MATERIALS CO., LTD. (TW) 2021-06-15 US disclosed
US-20210079161-A1 POLYIMIDE PRECURSOR COMPOSITION, USE THEREOF AND POLYIMIDE MADE THEREFROM ETERNAL MATERIALS CO., LTD. (TW) 2021-03-18 US disclosed
US-10731004-B2 Polyimide precursor composition and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2020-08-04 US disclosed
US-10696793-B2 Process for preparing polyimides ETERNAL MATERIALS CO., LTD. (TW) 2020-06-30 US disclosed
US-10626220-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2020-04-21 US disclosed
US-20100086871-A1 PHOTOSENSITIVE POLYIMIDES ETERNAL CHEMICAL CO., LTD. 2010-04-08 US disclosed
US-20100086874-A1 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2010-04-08 US disclosed
US-20100086874-A1 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2010-04-08 US disclosed
WO-2010001780-A1 HEAT-RESISTANT RESIN PRECURSOR AND PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME 旭化成イーマテリアルズ株式会社 (JP) 2010-01-07 WO disclosed
US-20090181324-A1 PHOTOSENSITIVE POLYIMIDES ETERNAL CHEMICAL CO., LTD. 2009-07-16 US disclosed
US-20090181324-A1 PHOTOSENSITIVE POLYIMIDES ETERNAL CHEMICAL CO., LTD. 2009-07-16 US disclosed
US-20080103275-A1 Negative photosensitive polyimide polymer and uses thereof ETERNAL CHEMICAL CO., LTD. 2008-05-01 US disclosed
US-20080103275-A1 Negative photosensitive polyimide polymer and uses thereof ETERNAL CHEMICAL CO., LTD. 2008-05-01 US disclosed
US-20080096997-A1 Amic acid ester oligomer precursor composition for polyimide resin containing the same, and uses ETERNAL MATERIALS CO., LTD. (TW) 2008-04-24 US disclosed
US-20080096997-A1 Amic acid ester oligomer precursor composition for polyimide resin containing the same, and uses ETERNAL MATERIALS CO., LTD. (TW) 2008-04-24 US disclosed