SCHEMBL16707367

SCHEMBL16707367

Cc1cc(C)c(C(F)(F)F)c(C)c1C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10001976 0.83 PGK1 (0.33) PGK1PGK2
SCHEMBL16707368 0.80 NOTUM (0.30)
SCHEMBL15574572 0.78
SCHEMBL24716330 0.78 CYP1A2 (0.35)
SCHEMBL10001971 0.73 AR (0.30)
SCHEMBL10994353 0.72 RAPGEF4 (0.43) PGK1PGK2
SCHEMBL13199207 0.72 RAPGEF4 (0.43)
SCHEMBL7202442 0.72 ALDH1A1 (0.37)
SCHEMBL13550031 0.70 RAPGEF4 (0.32)
SCHEMBL13816869 0.70 TRPA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647218-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-05-09 US disclosed
US-20150129849-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-05-14 US disclosed