SCHEMBL1000280

SCHEMBL1000280

[c]1ccc2oc3ccc(-c4ccccc4)cc3c2c1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.43
PLA2G4A P47712 4/20 0.43
PLA2G10 O15496 1/20 0.38
PRKDC P78527 3/20 0.37
PGR P06401 1/20 0.37
GAA P10253 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
PTPN1 P18031 2/20 0.35
PTPN2 P17706 1/20 0.35
TBK1 Q9UHD2 1/20 0.34
ALOX5 P09917 1/20 0.34
WEE1 P30291 1/20 0.34
MAP4K4 O95819 1/20 0.33
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL997082 0.83 MAPT (0.39) PLA2G2APLA2G4AGAAL3MBTL1KDM4E
SCHEMBL9889863 0.81 PLA2G2A (0.55) PLA2G2APLA2G4APLA2G10PRKDCPGR
SCHEMBL9889816 0.81 PLA2G2A (0.55) PLA2G2APLA2G4APLA2G10PRKDCPGR
SCHEMBL9889862 0.81 PLA2G2A (0.55) PLA2G2APLA2G4APLA2G10PRKDCPGR
SCHEMBL9889838 0.81 PLA2G2A (0.55) PLA2G2APLA2G4APLA2G10PRKDCPGR
SCHEMBL9889861 0.79 PLA2G2A (0.53) PLA2G2APLA2G4APLA2G10PRKDCPGR
SCHEMBL9889852 0.78 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10PRKDCPGR
SCHEMBL9889853 0.78 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10PRKDCPGR
SCHEMBL9889864 0.78 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10PRKDCPGR
SCHEMBL9889914 0.78 PLA2G2A (0.51) PLA2G2APLA2G4APLA2G10PRKDCPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2298737-B1 Indole compounds and organic light-emitting device including the same SAMSUNG DISPLAY CO LTD (KR) 2017-05-10 EP disclosed
EP-2085382-B1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO (JP) 2016-04-20 EP disclosed
US-9051328-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-09 US disclosed
US-8895159-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-25 US disclosed
US-8580393-B2 Polymer and organic electroluminescent device including the same IDEMITSU KOSAN CO., LTD. (JP) 2013-11-12 US disclosed
US-8524380-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2013-09-03 US disclosed
US-20130187137-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-07-25 US disclosed
EP-2293650-B1 Dipyrrolo[a,h]pyrenes for organic light-emitting devices SAMSUNG DISPLAY CO LTD (KR) 2013-03-27 EP disclosed
US-8399880-B2 Heteroarylamine compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2013-03-19 US disclosed
US-8394510-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-03-12 US disclosed
EP-2293650-A1 Dipyrrolo[a,h]pyrenes for organic light-emitting devices Samsung Mobile Display Co., Ltd. (KR) 2011-03-09 EP disclosed
EP-2292602-A1 Phenaleno[1,9-fg]indole based organic light-emitting devices Samsung Mobile Display Co., Ltd. (KR) 2011-03-09 EP disclosed
US-20110049488-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110049484-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110049494-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110049490-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110017983-A1 POLYMER AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME IDEMITSU KOSAN CO., LTD. 2011-01-27 US disclosed
US-20100219400-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 US disclosed
EP-2085382-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-08-05 EP disclosed
US-20080124572-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110049494-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME INMT, TYR, HTT PLA2G2A 3278/4885PLA2G4A 2382/4885PLA2G10 3054/4885
US-20110049490-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME TRPC1, TRPC4, LAGE3 PLA2G2A 4017/4885PLA2G4A 3843/4885PLA2G10 4468/4885
US-20110049484-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME INMT, TYR, HTT PLA2G2A 3278/4885PLA2G4A 2382/4885PLA2G10 3054/4885
US-20110049488-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME TRPC1, TRPC4, LAGE3 PLA2G2A 4017/4885PLA2G4A 3843/4885PLA2G10 4468/4885
US-20080124572-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, DDC, AOC2 PLA2G2A 4428/4885PLA2G4A 4719/4885PLA2G10 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.