Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042363 | 0.86 | RAB9A (0.63) | HSD17B10MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9040818 | 0.83 | MAPT (0.52) | HSD17B10MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3337498 | 0.83 | HSD17B10 (0.53) | HSD17B10MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10291489 | 0.81 | ALDH1A1 (0.51) | HSD17B10MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3345659 | 0.80 | HSD17B10 (0.55) | HSD17B10MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10004971 | 0.79 | HSD17B10 (0.54) | HSD17B10MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29874275 | 0.76 | TP53 (0.76) | HSD17B10MAPTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL24166923 | 0.75 | KDM4E (0.72) | HSD17B10MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9617482 | 0.75 | PTGS2 (0.69) | HSD17B10MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13490141 | 0.75 | PTGS2 (0.58) | HSD17B10MAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700906-A1 | Heterocyclic derivatives of N-phenylamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-13 | — | — | EP | claimed |
| US-5496826-A | ANTICONVULSANTS, MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-05 | — | — | US | claimed |
| EP-0700906-A1 | Heterocyclic derivatives of N-phenylamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5496826-A | ANTICONVULSANTS, MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-05 | — | — | US | disclosed |