Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405654 | 1.00 | KMT2A (0.86) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 | |
| SCHEMBL136513 | 1.00 | KMT2A (0.86) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 | |
| SCHEMBL724000 | 1.00 | KMT2A (0.86) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 | |
| SCHEMBL47043 | 1.00 | KMT2A (0.86) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL7862302 | 0.98 | KMT2A (0.83) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL224806 | 0.98 | KMT2A (0.83) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL10522089 | 0.98 | KMT2A (0.83) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL224805 | 0.98 | KMT2A (0.83) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 | |
| SCHEMBL47235 | 0.92 | KMT2A (1.00) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 | |
| SCHEMBL13223423 | 0.92 | KMT2A (1.00) | KMT2AKDM4ECYP2D6CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283475-A | Pentamethine thiopyrylium salts, process for production thereof, and photoconductive compositions containing said salts | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-11 | — | — | US | claimed |
| US-20200263231-A1 | Fluorogenic dyes for high sensitivity DNA detection | Life Technologies Corporation | 2020-08-20 | — | — | US | disclosed |
| EP-2408863-B1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORP (US) | 2018-01-10 | — | — | EP | disclosed |
| US-9458499-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-9382425-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2016-07-05 | — | — | US | disclosed |
| US-20160083782-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-03-24 | — | — | US | disclosed |
| US-9206474-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-20150031579-A1 | Aza-Benzazolium Containing Cyanine Dyes | MOLECULAR PROBES, INC. | 2015-01-29 | — | — | US | disclosed |
| US-8883415-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2014-11-11 | — | — | US | disclosed |
| US-20140178882-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORPORATION (US) | 2014-06-26 | — | — | US | disclosed |
| US-6458967-B1 | REACTING ACETYLENE COMPOUNDS TO FORM ENOL ETHER; REACTING WITH SULFUR OR SELENIUM OR TELLURIUM COMPOUND TO FORM DYE PRODUCT | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-10-01 | — | — | US | disclosed |
| US-20020022723-A1 | Method for preparation of an intermediate dye product | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE STATE UNIVERSITY OF NEW YORK AT BUFFALO | 2002-02-21 | — | — | US | disclosed |
| WO-2002000642-A1 | METHOD FOR PREPARATION OF AN INTERMEDIATE DYE PRODUCT | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2002-01-03 | — | — | WO | disclosed |
| EP-0675924-B1 | CYCLIC-SUBSTITUTED UNSYMMETRICAL CYANINE DYES | MOLECULAR PROBES INC (US) | 2001-12-12 | — | — | EP | disclosed |
| US-5658751-A | SUBSTITUENTS ON PYRIDINIUM OR QUINOLINIUM RING SYSTEM SERVE TO INCREASE OR DECREASE PERMEABILITY, SELECTIVITY AND BINDING AFFINITY OF NUCLEIC ACID STAINS; FORM FLUORESCENT COMPLEXES WITH NUCLEIC ACIDS | MOLECULAR PROBES, INC. (US) | 1997-08-19 | — | — | US | disclosed |
| US-5545535-A | USING MIXTURE OF FLUORESCENT DYES | MOLECULAR PROBES, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5436134-A | Fluorescent dyes for nucleic acids | MOLECULAR PROBES, INC. (US) | 1995-07-25 | — | — | US | disclosed |
| US-4663260-A | SEMICONDUCTOR LASER WAVELENGTHS | FUJI PHOTO FILM CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4283475-A | Pentamethine thiopyrylium salts, process for production thereof, and photoconductive compositions containing said salts | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022723-A1 | Method for preparation of an intermediate dye product | SRD5A1, SRD5A2, RER1 | KMT2A 2804/4885KDM4E 3201/4885CYP2D6 623/4885 |
| US-20200263231-A1 | Fluorogenic dyes for high sensitivity DNA detection | POLRMT, POLM, DNMT3A | KMT2A 1550/4885KDM4E 3509/4885CYP2D6 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.