SCHEMBL47043

SCHEMBL47043

C(=C/Nc1ccccc1)\C=N\c1ccccc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.86
KDM4E B2RXH2 2/20 0.54
CYP2D6 P10635 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 6/20 0.40
NPC1 O15118 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 3/20 0.36
CYP1A1 P04798 1/20 0.36
TSHR P16473 1/20 0.36
CYP1B1 Q16678 1/20 0.36
MEN1 O00255 4/20 0.35
IDO1 P14902 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405654 1.00 KMT2A (0.86) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL1000845 1.00 KMT2A (0.86) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL136513 1.00 KMT2A (0.86) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL724000 1.00 KMT2A (0.86) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL7862302 0.98 KMT2A (0.83) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL224806 0.98 KMT2A (0.83) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL10522089 0.98 KMT2A (0.83) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL224805 0.98 KMT2A (0.83) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL47235 0.92 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL13223423 0.92 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957293-B Guanine-based cyanine probe for specific recognition of insulin and method for preparing same 常州大学 2023-07-25 CN claimed
CN-113831358-B Cyanine probe based on adenine and preparation method and application thereof 常州大学 2022-03-25 CN claimed
EP-3655408-B1 CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE US HEALTH (US) 2021-07-14 EP claimed
US-10994029-B2 Conformational restriction of cyanine fluorophores in far-red and near-IR range THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2021-05-04 US claimed
US-20200179536-A1 CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2020-06-11 US claimed
US-12624391-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2026-05-12 US disclosed
EP-4680677-A1 BENZOTHIENOPYRROLE CYANINE DYES Beckman Coulter, Inc. (US) 2026-01-21 EP disclosed
EP-4583845-A1 PROGRAMMABLE STIMULI-RESPONSIVE POLYMERIC FORMULATIONS Ramot at Tel-Aviv University Ltd. (IL) 2025-07-16 EP disclosed
WO-2024196805-A1 BENZOTHIENOPYRROLE CYANINE DYES BECKMAN COULTER, INC. (US) 2024-09-26 WO disclosed
US-20240132948-A1 Cyanine Dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2024-04-25 US disclosed
WO-2024052920-A1 PROGRAMMABLE STIMULI-RESPONSIVE POLYMERIC FORMULATIONS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-03-14 WO disclosed
US-11813338-B2 Diagnosing and treating cancer THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-11-14 US disclosed
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2007-07-26 US disclosed
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2007-07-26 US disclosed
US-20070042295-A1 Optical data carrier comprising a polymeric network in the information layer LANXESS DEUTSCHLAND GMBH (DE) 2007-02-22 US disclosed
US-20070042295-A1 Optical data carrier comprising a polymeric network in the information layer LANXESS DEUTSCHLAND GMBH (DE) 2007-02-22 US disclosed
US-7161010-B2 Methine dyes; coloring compound FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 US disclosed
US-7161010-B2 Methine dyes; coloring compound FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 US disclosed
US-20070004923-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2007-01-04 US disclosed
US-20070004923-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132948-A1 Cyanine Dyes ABCG2, IK, ACR KMT2A 2564/4885KDM4E 2687/4885CYP2D6 1589/4885
US-20070004923-A1 Methine compound and silver halide photographic material containing the same PYM1, NPM1, METTL3 KMT2A 96/4885KDM4E 2044/4885CYP2D6 1470/4885
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates PHOSPHO1, PFAS, PHPT1 KMT2A 3091/4885KDM4E 4173/4885CYP2D6 3524/4885
US-10994029-B2 Conformational restriction of cyanine fluorophores in far-red and near-IR range IK, FAR1, SPR KMT2A 3016/4885KDM4E 2935/4885CYP2D6 1684/4885
US-20200179536-A1 CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE IK, FAR1, SPR KMT2A 3016/4885KDM4E 2935/4885CYP2D6 1684/4885
US-11813338-B2 Diagnosing and treating cancer CHKA, CHKB, CILK1 KMT2A 805/4885KDM4E 1398/4885CYP2D6 4305/4885
US-12624391-B2 Cyanine dyes POLL, POLR2E, POLR2H KMT2A 2631/4885KDM4E 3684/4885CYP2D6 1523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.