SCHEMBL136513

SCHEMBL136513

C(=CNc1ccccc1)C=Nc1ccccc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.86
KDM4E B2RXH2 2/20 0.54
CYP2D6 P10635 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 6/20 0.40
NPC1 O15118 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 3/20 0.36
CYP1A1 P04798 1/20 0.36
TSHR P16473 1/20 0.36
CYP1B1 Q16678 1/20 0.36
MEN1 O00255 4/20 0.35
IDO1 P14902 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405654 1.00 KMT2A (0.86) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL1000845 1.00 KMT2A (0.86) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL724000 1.00 KMT2A (0.86) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL47043 1.00 KMT2A (0.86) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL7862302 0.98 KMT2A (0.83) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL224806 0.98 KMT2A (0.83) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL10522089 0.98 KMT2A (0.83) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL224805 0.98 KMT2A (0.83) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL47235 0.92 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9
SCHEMBL13223423 0.92 KMT2A (1.00) KMT2AKDM4ECYP2D6CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462479-A For detecting ONOO-/ClO-Preparation of low background nanoprobe and whole blood detection 湖南师范大学 2025-02-18 CN claimed
CN-114249986-A Preparation method of near-infrared fluorescent compound based on pentamethyl cyanine dye as skeleton 天津科技大学 2022-03-29 CN claimed
US-4283475-A Pentamethine thiopyrylium salts, process for production thereof, and photoconductive compositions containing said salts FUJI PHOTO FILM CO., LTD. (JP) 1981-08-11 US claimed
CN-122036584-A Fluorescent dye compound and preparation method and application thereof 深圳大学 2026-05-15 CN disclosed
US-12624391-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2026-05-12 US disclosed
EP-4583845-A1 PROGRAMMABLE STIMULI-RESPONSIVE POLYMERIC FORMULATIONS Ramot at Tel-Aviv University Ltd. (IL) 2025-07-16 EP disclosed
CN-114805310-B Fluorescent compounds containing hydroxy-substituted triazines and methods of making the same 佰爱特有限公司 2024-07-26 CN disclosed
CN-118165544-A Pentamethine cyanine dye fluorescent probe synthesis and application suitable for dynamic super-resolution imaging of cell membranes 中国科学院大连化学物理研究所 2024-06-11 CN disclosed
US-20240132948-A1 Cyanine Dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2024-04-25 US disclosed
WO-2024052920-A1 PROGRAMMABLE STIMULI-RESPONSIVE POLYMERIC FORMULATIONS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-03-14 WO disclosed
US-11624089-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-04-11 US disclosed
EP-0295698-A2 Silver halide photographic light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1988-12-21 EP disclosed
US-4663260-A SEMICONDUCTOR LASER WAVELENGTHS FUJI PHOTO FILM CO., LTD. (JP) 1987-05-05 US disclosed
US-4551420-A ULTRAVIOLET RAY ABSORBING POLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1985-11-05 US disclosed
US-4464462-A ULTRAVIOLET RAY-ABSORBING ACRYLIC POLYMER LATEX; ANTISTATIC AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1984-08-07 US disclosed
US-4455368-A Silver halide photographic light-sensitive material containing a UV absorbing polymer latex FUJI PHOTO FILM CO., LTD. (JP) 1984-06-19 US disclosed
US-4443534-A VINYL CHLORIDE HOMO- OR COPOLYMER, OR ACRYLAMIDE OR ACRYLIC ESTER HOMO- OR COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1984-04-17 US disclosed
US-4283475-A Pentamethine thiopyrylium salts, process for production thereof, and photoconductive compositions containing said salts FUJI PHOTO FILM CO., LTD. (JP) 1981-08-11 US disclosed
US-4239901-A ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1980-12-16 US disclosed
US-4195999-A Silver halide photographic material containing ultraviolet light absorbing agent FUJI PHOTO FILM CO., LTD. (JP) 1980-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132948-A1 Cyanine Dyes ABCG2, IK, ACR KMT2A 2564/4885KDM4E 2687/4885CYP2D6 1589/4885
US-11624089-B2 Cyanine dyes ABCG2, IK, ACR KMT2A 2564/4885KDM4E 2687/4885CYP2D6 1589/4885
US-12624391-B2 Cyanine dyes POLL, POLR2E, POLR2H KMT2A 2631/4885KDM4E 3684/4885CYP2D6 1523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.