SCHEMBL10012155

SCHEMBL10012155

CCOC(=O)CC(OC=O)C(=O)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
CYP3A4 P08684 3/20 0.42
ALOX15 P16050 3/20 0.42
HSD17B10 Q99714 3/20 0.42
CHRM1 P11229 1/20 0.42
ADORA1 P30542 1/20 0.42
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
TSHR P16473 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
TRPA1 O75762 1/20 0.39
CYP2D6 P10635 2/20 0.36
NR1I2 O75469 1/20 0.35
PGR P06401 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
PTGS2 P35354 1/20 0.35
PDE4D Q08499 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10012012 0.81 ALDH1A1 (0.43) ALDH1A1HSD17B10TSHR
SCHEMBL10593569 0.80 ALDH1A1 (0.37) ALDH1A1ALOX15HSD17B10MGAMGAA
SCHEMBL4984393 0.78 MGAM (0.46) ALDH1A1CYP3A4ALOX15HSD17B10CHRM1
SCHEMBL22040635 0.78 MGAM (0.46) ALDH1A1CYP3A4ALOX15HSD17B10CHRM1
SCHEMBL1245715 0.78 ALDH1A1 (0.50) ALDH1A1CYP3A4ALOX15HSD17B10CHRM1
SCHEMBL10011326 0.77 MET (0.35) ALDH1A1CYP3A4ALOX15HSD17B10CHRM1
SCHEMBL13136942 0.76 ALDH1A1 (0.53) ALDH1A1CYP3A4ALOX15HSD17B10CHRM1
SCHEMBL10979567 0.74 ALDH1A1 (0.44) ALDH1A1CYP3A4ALOX15HSD17B10CHRM1
SCHEMBL10010403 0.74 ALDH1A1 (0.44) ALDH1A1CYP3A4ALOX15HSD17B10CHRM1
SCHEMBL10012399 0.74 TSHR (0.36) HSD17B10MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624309-B2 Enol ether properfume FIRMENICH SA (CH) 2026-05-12 US disclosed
EP-4139274-B1 ENOL ETHER PROPERFUME FIRMENICH & CIE (CH) 2024-02-14 EP disclosed
US-20230220298-A1 ENOL ETHER PROPERFUME FIRMENICH & CIE (CH) 2023-07-13 US disclosed
EP-4139274-A1 ENOL ETHER PROPERFUME Firmenich SA (CH) 2023-03-01 EP disclosed
CN-115702138-A Enol ether pro-fragrances 弗门尼舍有限公司 2023-02-14 CN disclosed
WO-2021250164-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2021-12-16 WO disclosed
CN-103097387-B Ring-fused pyrimidines and triazines and use thereof for treating and/or preventing cardiovascular diseases 拜耳知识产权有限责任公司 2016-11-02 CN disclosed
US-9130244-B2 Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES, LTD. (JP) 2015-09-08 US disclosed
EP-2908376-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2015-08-19 EP disclosed
CN-104812762-A Substituted annulated pyrimidines and triazines, and use thereof Bayer Pharma AG 2015-07-29 CN disclosed
EP-2479831-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2012-07-25 EP disclosed
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed
CN-101432129-A Novel compounds that are useful for improving pharmacokinetics ABBOTT LAB (US) 2009-05-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220298-A1 ENOL ETHER PROPERFUME CYP2E1, ADH5, ECI1 ALDH1A1 107/4885CYP3A4 28/4885ALOX15 314/4885
US-20120171581-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME SLC8A1, OR10J3, SLC8B1 ALDH1A1 2965/4885CYP3A4 3038/4885ALOX15 1722/4885
US-12624309-B2 Enol ether properfume CYP2E1, CBR1, ADH5 ALDH1A1 33/4885CYP3A4 24/4885ALOX15 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.