SCHEMBL10013486

SCHEMBL10013486

COc1ccc(C(C)(c2ccc(OC)cc2)C(F)(F)F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
HSD11B1 P28845 1/20 0.50
CA12 O43570 1/20 0.50
CA14 Q9ULX7 1/20 0.50
AHR P35869 1/20 0.44
RAB9A P51151 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
PDK1 Q15118 1/20 0.43
PDK2 Q15119 1/20 0.43
PDK3 Q15120 1/20 0.43
PDK4 Q16654 1/20 0.43
MAPT P10636 3/20 0.43
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 4/20 0.42
MAPK1 P28482 3/20 0.42
ALDH1A1 P00352 2/20 0.42
RECQL P46063 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12426024 0.92 ACHE (0.58) CA1CA2CA7CA9HSD11B1
SCHEMBL10705111 0.92 CA4 (0.48) CA1CA2CA7CA9HSD11B1
SCHEMBL12793169 0.86 CA1 (0.55) CA1CA2CA7CA9HSD11B1
SCHEMBL20364914 0.84 HSD11B1 (0.50) CA1CA2CA9HSD11B1PDK1
SCHEMBL1246270 0.82 CA1 (0.50) CA1CA2CA7CA9HSD11B1
SCHEMBL6818771 0.82 CA1 (0.50) CA1CA2CA7CA9HSD11B1
SCHEMBL9072846 0.81 CA1 (0.55) CA1CA2CA7CA9HSD11B1
SCHEMBL689878 0.79 CA1 (0.52) CA1CA2CA7CA9HSD11B1
SCHEMBL2616610 0.79 CA1 (0.52) CA1CA2CA7CA9HSD11B1
SCHEMBL11356774 0.79 CA1 (0.52) CA1CA2CA7CA9HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9834644-B1 Photomechanically active copolyimides derived from an azobenzenediamine, a rigid dianhydride, and a flexible dianhydride THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2017-12-05 US disclosed
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2017-09-14 US disclosed
US-9761804-B2 Oligomeric organic light emitting diode (OLED) materials containing multiple crosslinking functions LOMOX LIMITED (GB) 2017-09-12 US disclosed
US-9695284-B2 Polymer and thermosetting composition containing same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2017-07-04 US disclosed
US-20160313641-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITIONS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2016-10-27 US disclosed
US-9224971-B2 Organic electroluminescence device and display unit JOLED INC. (JP) 2015-12-29 US disclosed
US-20150219990-A1 Novel Polyimide Compositions FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2015-08-06 US disclosed
US-9085661-B1 Photomechanically active copolyimides derived from an azobenzenediamine, a rigid dianhydride, and a flexible dianhydride THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2015-07-21 US disclosed
US-20140343199-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2014-11-20 US disclosed
US-8124241-B2 Process for producing multilayer polymide film KANEKA CORPORATION (JP) 2012-02-28 US disclosed
US-8124241-B2 Process for producing multilayer polymide film KANEKA CORPORATION (JP) 2012-02-28 US disclosed
US-20110127505-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND DISPLAY UNIT SONY CORPORATION (JP) 2011-06-02 US disclosed
US-20090104465-A1 Process for Producing Multilayered Polyimide Film KANEKA CORPORATION (JP) 2009-04-23 US disclosed
US-20090104465-A1 Process for Producing Multilayered Polyimide Film KANEKA CORPORATION (JP) 2009-04-23 US disclosed
US-20090022939-A1 Adhesive Film KANEKA CORPORATION (JP) 2009-01-22 US disclosed
US-20090022939-A1 Adhesive Film KANEKA CORPORATION (JP) 2009-01-22 US disclosed
WO-2008017318-A1 OPTICAL DEVICE AND POLYMER MATERIAL WITH NONLINEAR OPTICAL PROPERTIES PIRELLI & C. S.P.A. (IT) 2008-02-14 WO disclosed
US-20070065700-A1 High temperature polymer electrolyte membranes SRI INTERNATIONAL 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same INO80C, INCENP, PUF60 CA1 2827/4885CA2 3720/4885CA7 2567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.