Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 8/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013486 | 0.92 | CA1 (0.50) | AHRHSD11B1ALDH1A1LMNAMAPT | |
| SCHEMBL12426024 | 0.85 | ACHE (0.58) | KIF11AHRHSD11B1MAPTCA12 | |
| SCHEMBL5079313 | 0.83 | ALDH1A1 (0.52) | KIF11HSD11B1ALDH1A1MAPTCA1 | |
| SCHEMBL12737709 | 0.82 | CA4 (0.50) | CA4KIF11KCNH2LTA4HAHR | |
| SCHEMBL11365690 | 0.82 | CA4 (0.50) | CA4KIF11KCNH2LTA4HAHR | |
| SCHEMBL2324555 | 0.82 | CA4 (0.54) | CA4KIF11KCNH2LTA4HAHR | |
| SCHEMBL29360224 | 0.82 | CA4 (0.54) | CA4KIF11KCNH2LTA4HAHR | |
| SCHEMBL16626130 | 0.82 | CA4 (0.54) | CA4KIF11KCNH2LTA4HAHR | |
| SCHEMBL4570566 | 0.79 | CA4 (0.56) | CA4KIF11KCNH2LTA4HTRPA1 | |
| SCHEMBL2689280 | 0.79 | CA4 (0.56) | CA4KIF11KCNH2LTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157679-B1 | ORGANIC COMPOUND SHOWING A SMECTIC PHASE A, MIXTURE CONTAINING THIS COMPOUND AND PROCESS FOR MAKING IT | THOMSON-CSF (FR) | 1988-05-18 | — | — | EP | disclosed |
| EP-0157679-A1 | Organic compound showing a smectic phase A, mixture containing this compound and process for making it | THOMSON-CSF (FR) | 1985-10-09 | — | — | EP | disclosed |