SCHEMBL2616610

SCHEMBL2616610

COc1ccc(C(c2ccc(OC)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA14 Q9ULX7 1/20 0.52
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
HSD11B1 P28845 1/20 0.47
RAB9A P51151 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ACHE P22303 1/20 0.44
ALDH1A1 P00352 2/20 0.43
CYP2A6 P11509 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
MAPK1 P28482 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10112762 1.00 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL7938513 0.92 NFE2L2 (0.52) CA1CA2CA7CA9CA12
SCHEMBL9914241 0.92 ACHE (0.60) CA1CA2CA7CA9CA12
SCHEMBL18715511 0.92 MAPT (0.51) CA1CA2CA7CA9CA12
SCHEMBL12737709 0.92 CA4 (0.50) CA1CA2CA7CA9CA12
SCHEMBL19335942 0.90 CA1 (0.42) CA1CA2CA7CA9CA12
SCHEMBL7929343 0.90 ESR2 (0.69) CA1CA2CA7CA9CA12
SCHEMBL12277221 0.87 ACHE (0.54) CA1CA2CA7CA9CA12
SCHEMBL12260130 0.87 ACHE (0.54) CA1CA2CA7CA9CA12
SCHEMBL14191202 0.85 NPSR1 (0.43) CA1CA2CA7CA9HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338906-A1 SEPARATION MEMBRANE NITTO DENKO CORPORATION (JP) 2023-10-26 US disclosed
WO-2023176172-A1 POLYIMIDE RESIN PRECURSOR 東京応化工業株式会社 2023-09-21 WO disclosed
US-20230244148-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-08-03 US disclosed
US-20230235115-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-07-27 US disclosed
US-20230235115-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-07-27 US disclosed
EP-4215262-A1 SEPARATION MEMBRANE NITTO DENKO CORPORATION (JP) 2023-07-26 EP disclosed
US-20230146282-A1 METAL ORGANIC FRAMEWORK, SEPARATION MEMBRANE, AND METHOD FOR PRODUCING METAL ORGANIC FRAMEWORK NITTO DENKO CORPORATION (JP) 2023-05-11 US disclosed
US-20230146282-A1 METAL ORGANIC FRAMEWORK, SEPARATION MEMBRANE, AND METHOD FOR PRODUCING METAL ORGANIC FRAMEWORK NITTO DENKO CORPORATION (JP) 2023-05-11 US disclosed
US-20230130077-A1 SEPARATION MEMBRANE NITTO DENKO CORPORATION (JP) 2023-04-27 US disclosed
US-20230130077-A1 SEPARATION MEMBRANE NITTO DENKO CORPORATION (JP) 2023-04-27 US disclosed
US-20070218277-A1 Adhesive Film, Flexible Metal-Clad Laminate, and Processes for Producing These KANEKA CORPORATION (JP) 2007-09-20 US disclosed
US-20070218277-A1 Adhesive Film, Flexible Metal-Clad Laminate, and Processes for Producing These KANEKA CORPORATION (JP) 2007-09-20 US disclosed
US-7267883-B2 Polyimide film and laminate having metal layer and same KANEKA CORPORATION (JP) 2007-09-11 US disclosed
US-7267883-B2 Polyimide film and laminate having metal layer and same KANEKA CORPORATION (JP) 2007-09-11 US disclosed
US-20070196734-A1 Ion-Conducting Polymers And Membranes Comprising Them Johnson Matthey Hydrogen Technologies Limited (GB) 2007-08-23 US disclosed
US-20070178323-A1 Polyimide multilayer body and method for producing same KANEKA CORPORATION (JP) 2007-08-02 US disclosed
US-20070178323-A1 Polyimide multilayer body and method for producing same KANEKA CORPORATION (JP) 2007-08-02 US disclosed
US-20070149727-A1 Moisture-curable resin composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2007-06-28 US disclosed
US-7229732-B2 Imaging members with crosslinked polycarbonate in charge transport layer XEROX CORPORATION (US) 2007-06-12 US disclosed
US-20070105030-A1 1, 4-Benzodioxane sulfonic acid compound and use thereof as electron-acceptor material NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105030-A1 1, 4-Benzodioxane sulfonic acid compound and use thereof as electron-acceptor material USE1, SLC9A1, ELOVL1 CA1 1202/4885CA2 1456/4885CA7 944/4885
US-20230146282-A1 METAL ORGANIC FRAMEWORK, SEPARATION MEMBRANE, AND METHOD FOR PRODUCING METAL ORGANIC FRAMEWORK SLCO4C1, SLCO2B1, SLCO1A2 CA1 280/4885CA2 61/4885CA7 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.