Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5606345

Cl.N=c1ccc2c(-c3ccccc3C(=O)O)c3ccc(N)cc3oc-2c1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 2/20 0.37
USP2 O75604 5/20 0.76
ATM Q13315 2/20 0.76
CFTR P13569 1/20 0.76
PAX8 Q06710 1/20 0.76
GOPC Q9HD26 1/20 0.76
ABCB1 P08183 1/20 0.76
L3MBTL1 Q9Y468 1/20 0.56
FTO Q9C0B1 2/20 0.45
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
POLB P06746 3/20 0.42
ALPL P05186 1/20 0.42
ALPI P09923 1/20 0.42
ALPG P10696 1/20 0.42
GNG2 P59768 1/20 0.41
GNB1 P62873 1/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29376502 1.00 USP2 (0.76) USP2ATMCFTRPAX8GOPC
SCHEMBL458205 0.99 ABCB1 (0.77) USP2ATMCFTRPAX8GOPC
Sulfuric Acid SCHEMBL16593429 0.95 ABCB1 (0.71) USP2ATMCFTRPAX8GOPC
Sulfuric Acid SCHEMBL16593427 0.92 ABCB1 (0.68) USP2ATMCFTRPAX8GOPC
SCHEMBL23309754 0.89 ABCB1 (0.76) USP2ATMCFTRPAX8GOPC
SCHEMBL9979456 0.89 ABCB1 (0.79) USP2ATMCFTRPAX8GOPC
SCHEMBL14693687 0.89 ABCB1 (0.76) USP2ATMCFTRPAX8GOPC
Hydrochloric Acid SCHEMBL18816029 0.87 USP2 (0.98) USP2ATMCFTRPAX8GOPC
Hydrochloric Acid SCHEMBL29363314 0.87 USP2 (0.98) USP2ATMCFTRPAX8GOPC
Hydrochloric Acid SCHEMBL3808879 0.87 USP2 (0.98) USP2ATMCFTRPAX8GOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124317-A2 Antibody Drug Conjugates BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
US-20250135026-A1 Antibody Drug Conjugates BEIGENE SWITZERLAND GMBH (CH) 2025-05-01 US disclosed
WO-2023125530-A1 ANTIBODY DRUG CONJUGATES BEIGENE, LTD. (KY) 2023-07-06 WO disclosed
EP-1566684-B1 LENS FOR EYE AND METHOD FOR MARKING THEREOF MENICON CO LTD (JP) 2007-03-14 EP disclosed
US-7044598-B2 Lens for eye and method for marking thereof MENICON CO., LTD.. (JP) 2006-05-16 US disclosed
US-20050206843-A1 Lens for eye and method for marking thereof MENICON CO., LTD. (JP) 2005-09-22 US disclosed
US-6555278-B1 Color filter array film EASTMAN KODAK COMPANY 2003-04-29 US disclosed
EP-0281381-B1 ELECTROLUMINESCENT DEVICE WITH MODIFIED THIN FILM LUMINESCENT ZONE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-07-15 EP disclosed
EP-0212450-B1 SOLID SCINTILLATOR COUNTING COMPOSITIONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-12-27 EP disclosed
EP-0349265-A2 Electroluminescent devices EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-01-03 EP disclosed
EP-0281381-A2 Electroluminescent device with modified thin film luminescent zone EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-09-07 EP disclosed
US-4769292-A Electroluminescent device with modified thin film luminescent zone EASTMAN KODAK COMPANY (US) 1988-09-06 US disclosed
US-4692266-A FOR USE IN LIQUIDS, FLUOR PARTICLES IN BINDER, POROSITY EASTMAN KODAK COMPANY (US) 1987-09-08 US disclosed
EP-0212450-A1 Solid scintillator counting compositions EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-03-04 EP disclosed
US-4357486-A Luminescent solar collector ATLANTIC RICHFIELD COMPANY (US) 1982-11-02 US disclosed
US-4251288-A SOLAR ENERGY ATLANTIC RICHFIELD COMPANY (US) 1981-02-17 US disclosed
US-4140544-A Divergent luminescent collector for photovoltaic device ATLANTIC RICHFIELD COMPANY (US) 1979-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124317-A2 Antibody Drug Conjugates SLC3A2, SLC7A1, SLC43A1 CA2 491/4885USP2 2417/4885ATM 2985/4885
US-20250135026-A1 Antibody Drug Conjugates CD22, FCGR2A, FCGR3B CA2 3412/4885USP2 1829/4885ATM 4246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.