SCHEMBL10014554

SCHEMBL10014554

c1ccc(-c2cc(-c3ccc(-n4c5ccccc5c5ccc6sc7ccccc7c6c54)cc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.37
MEN1 O00255 8/20 0.37
MAPT P10636 8/20 0.37
HPGD P15428 8/20 0.37
ALDH1A1 P00352 7/20 0.37
NTSR1 P30989 1/20 0.37
KDM4E B2RXH2 6/20 0.34
LMNA P02545 2/20 0.34
GLA P06280 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ATM Q13315 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
RXFP1 Q9HBX9 1/20 0.32
CYP2C19 P33261 1/20 0.32
PTK2B Q14289 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
MAPK1 P28482 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10014552 1.00 KMT2A (0.37) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL21018710 0.96 MEN1 (0.34) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL21017482 0.96 MEN1 (0.34) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL21018709 0.95 MEN1 (0.34) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL21017480 0.95 MEN1 (0.36) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL21017479 0.95 MEN1 (0.34) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL21018712 0.95 MEN1 (0.36) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL18564518 0.94 MEN1 (0.34) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL21018094 0.94 MEN1 (0.36) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL21017511 0.94 MEN1 (0.36) KMT2AMEN1MAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11569452-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-31 US disclosed
US-10991890-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same DUK SAN NEOLUX CO., LTD. (KR) 2021-04-27 US disclosed
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-12-26 US disclosed
US-20190157603-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-23 US disclosed
US-10297761-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-05-21 US disclosed
US-10020452-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-10020452-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-20160197286-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197286-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20150053960-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME DUK SAN NEOLUX CO., LTD. (KR) 2015-02-26 US disclosed
US-20150053960-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME DUK SAN NEOLUX CO., LTD. (KR) 2015-02-26 US disclosed
US-8889271-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same DUKSAN HIGH METAL CO., LTD. (KR) 2014-11-18 US disclosed
US-8889271-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same DUKSAN HIGH METAL CO., LTD. (KR) 2014-11-18 US disclosed
US-20140299865-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-09 US disclosed
US-20140299865-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-09 US disclosed
US-20140084270-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-27 US disclosed
US-20140084270-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-27 US disclosed
US-20120080670-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-05 US disclosed
US-20120080670-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10991890-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same NOTUM, OR10J3, PER2 KMT2A 1786/4885MEN1 1767/4885MAPT 2122/4885
US-10020452-B2 Compound containing a 5-membered heterocycle and organic light-emitting diode using same, and terminal for same NOTUM, OR10J3, PER2 KMT2A 1786/4885MEN1 1767/4885MAPT 2122/4885
US-11569452-B2 Organic light-emitting device CRY1, TRPA1, CRY2 KMT2A 3547/4885MEN1 3558/4885MAPT 126/4885
US-20190393424-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, LIN28A, OR51E2 KMT2A 2125/4885MEN1 2760/4885MAPT 1108/4885
US-20120080670-A1 COMPOUND CONTAINING A 5-MEMBERED HETEROCYCLE AND ORGANIC LIGHT-EMITTING DIODE USING SAME, AND TERMINAL FOR SAME NOTUM, OR10J3, PER2 KMT2A 1786/4885MEN1 1767/4885MAPT 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.