Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 7/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014736 | 0.81 | AKR1C3 (0.42) | FYNNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL10014735 | 0.79 | FYN (0.39) | HSD17B14NOTUMFYNTRPV3ALDH1A1 | |
| SCHEMBL10014743 | 0.77 | AKR1C3 (0.45) | ALDH1A1HSD17B10BRD4 | |
| SCHEMBL10014731 | 0.75 | KEAP1 (0.37) | HSD17B14NOTUMFYNTRPV3ALDH1A1 | |
| SCHEMBL12750058 | 0.75 | KDM4E (0.34) | ALDH1A1KDM4E | |
| SCHEMBL10014732 | 0.72 | FYN (0.43) | HSD17B14NOTUMFYNALDH1A1TSHR | |
| SCHEMBL10014729 | 0.71 | HSD17B14 (0.41) | HSD17B14FYNTRPV3ALDH1A1TSHR | |
| SCHEMBL10014746 | 0.69 | HSD17B14 (0.47) | HSD17B14FYNALDH1A1KDM4ENPC1 | |
| SCHEMBL30602821 | 0.68 | ALDH1A1 (0.58) | NOTUMFYNALDH1A1TSHRKDM4E | |
| SCHEMBL10014745 | 0.67 | HSD17B14 (0.40) | HSD17B14FYNALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | SOLVAY SA (BE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | PPIP5K2, HPRT1, PHPT1 | HSD17B14 4318/4885NOTUM 4610/4885FYN 3882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.