SCHEMBL17930252

SCHEMBL17930252

C=c1ccc2c(c1)Oc1cc(O)ccc1C=2c1cc(C(C)(C)C)ccc1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ USP2 O75604 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ HSP90AA1 P07900 1/20 0.38
▸ HSP90AB1 P08238 1/20 0.38
▸ BRCA1 P38398 1/20 0.38
▸ YWHAG P61981 1/20 0.38
▸ KEAP1 Q14145 1/20 0.38
▸ NFE2L2 Q16236 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ CA12 O43570 2/20 0.32
▸ CA1 P00915 2/20 0.32
▸ CA9 Q16790 2/20 0.32
▸ ESRRG P62508 1/20 0.31
▸ SERPINE1 P05121 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12171475 0.93 MEN1 (0.39) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL19749041 0.86 MEN1 (0.37) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL20411330 0.85 L3MBTL1 (0.37) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL12926177 0.82 MEN1 (0.53) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL12678084 0.81 HSD17B10 (0.38) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL19749039 0.80 HSD17B10 (0.35) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL14620246 0.79 HSD17B10 (0.39) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL19543149 0.77 HSD17B10 (0.36) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL20248671 0.77 HSD17B10 (0.36) MEN1KMT2ATDP1HSD17B10USP2
SCHEMBL10015993 0.77 FTO (0.33) MEN1KMT2ATDP1HSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207423-A1 PROGAMMABLE POLYMERIC DRUGS SONY GROUP CORP (JP) 2024-06-27 — — US disclosed
US-12018159-B2 Ultra bright dimeric or polymeric dyes and methods for preparation of the same Sony Group Corporation (JP) 2024-06-25 — — US disclosed
US-11874280-B2 Use of divalent metals for enhancement of fluorescent signals Sony Group Corporation (JP) 2024-01-16 — — US disclosed
US-11827661-B2 Water soluble fluorescent or colored dyes comprising conjugating groups Sony Group Corporation (JP) 2023-11-28 — — US disclosed
US-11685835-B2 Ultra bright dimeric or polymeric dyes SONY CORPORATION (JP) 2023-06-27 — — US disclosed
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-04-27 — — US disclosed
US-20180163052-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE Sony Group Corporation (JP) 2018-06-14 — — US disclosed
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2018-06-14 — — US disclosed
US-20180079909-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES SONY CORPORATION (JP) 2018-03-22 — — US disclosed
US-20180065998-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES COMPRISING CONJUGATING GROUPS Sony Group Corporation (JP) 2018-03-08 — — US disclosed
US-9851359-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2017-12-26 — — US disclosed
US-20170292957-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2017-10-12 — — US disclosed
US-9765220-B2 Water soluble fluorescent or colored dyes and methods for their use SONY CORPORATION (JP) 2017-09-19 — — US disclosed
US-20160208100-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE Sony Group Corporation (JP) 2016-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180163052-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE CHRM1, CHRM2, IK MEN1 705/4885KMT2A 3996/4885TDP1 1849/4885
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 MEN1 1209/4885KMT2A 2550/4885TDP1 1755/4885
US-20160208100-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE CHRM1, CHRM2, IK MEN1 705/4885KMT2A 3996/4885TDP1 1849/4885
US-20180065998-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES COMPRISING CONJUGATING GROUPS CHRM1, CHRM2, H1-0 MEN1 478/4885KMT2A 3330/4885TDP1 1731/4885
US-20240207423-A1 PROGAMMABLE POLYMERIC DRUGS OPRM1, CHRM1, TUBB3 MEN1 371/4885KMT2A 4292/4885TDP1 3696/4885
US-11827661-B2 Water soluble fluorescent or colored dyes comprising conjugating groups CHRM1, CHRM2, H1-0 MEN1 478/4885KMT2A 3330/4885TDP1 1731/4885
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 MEN1 1209/4885KMT2A 2550/4885TDP1 1755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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