Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.59 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 3/20 | 0.58 |
| ▸ | CNR2 | P34972 | 3/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454080 | 1.00 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 | |
| SCHEMBL10016656 | 1.00 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 | |
| SCHEMBL18428385 | 1.00 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 | |
| SCHEMBL3614630 | 1.00 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 | |
| SCHEMBL2089328 | 1.00 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 | |
| SCHEMBL10016663 | 1.00 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 | |
| SCHEMBL10016295 | 0.96 | CNR1 (0.58) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 | |
| SCHEMBL5673282 | 0.94 | CNR1 (0.59) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 | |
| SCHEMBL2089610 | 0.94 | CNR1 (0.59) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 | |
| SCHEMBL8372330 | 0.94 | CNR1 (0.59) | ZDHHC20ZDHHC2CNR1CNR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189350-B | Trans-2-decenoic acid derivative and drug containing same | NAGOYA INDUSTRIAL SCIENCE RESRARCH INSTITUTE (JP) | 2016-04-27 | — | — | CN | disclosed |
| US-20150297562-A1 | ANALGESIC | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150297562-A1 | ANALGESIC | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-8987486-B2 | Trans-2-decenoic acid derivative and pharmaceutical agent containing the same | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8987486-B2 | Trans-2-decenoic acid derivative and pharmaceutical agent containing the same | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2015-03-24 | — | — | US | disclosed |
| EP-2842553-A1 | ANALGESIC | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-2636666-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME | Nagoya Industrial Science Research Institute (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| WO-2012060396-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND MEDICAMENT CONTAINING SAME | 財団法人名古屋産業科学研究所 (JP) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297562-A1 | ANALGESIC | OPRK1, OPRL1, OPRD1 | ZDHHC20 1258/4885ZDHHC2 1003/4885CNR1 129/4885 |
| US-20130225837-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND PHARMACEUTICAL AGENT CONTAINING THE SAME | BDNF, NTRK2, NGF | ZDHHC20 1090/4885ZDHHC2 579/4885CNR1 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.