SCHEMBL10016653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15204996	1.00	PPARG (0.44)	PPARGPPARADNM1EPHX2ZDHHC20
	SCHEMBL15205394	0.92	PPARG (0.45)	PPARGPPARAEPHX2TERTMAPT
	SCHEMBL10016646	0.92	PPARG (0.45)	PPARGPPARAEPHX2TERTMAPT
	SCHEMBL15205175	0.90	ZDHHC20 (0.50)	PPARGPPARAEPHX2ZDHHC20TERT
	SCHEMBL10016662	0.90	ZDHHC20 (0.50)	PPARGPPARAEPHX2ZDHHC20TERT
	SCHEMBL28066861	0.90	ZDHHC20 (0.50)	PPARGPPARAEPHX2ZDHHC20TERT
	SCHEMBL15216629	0.90	PPARG (0.49)	PPARGPPARAZDHHC20TERTMAPT
	SCHEMBL27992461	0.90	PPARG (0.49)	PPARGPPARAZDHHC20TERTMAPT
	SCHEMBL8036393	0.90	ZDHHC20 (0.50)	PPARGPPARAEPHX2ZDHHC20TERT
	SCHEMBL10016640	0.90	ZDHHC20 (0.50)	PPARGPPARAEPHX2ZDHHC20TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.