Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 3/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | CNR1 | P21554 | 1/20 | 0.70 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14291945 | 0.92 | MEN1 (0.83) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1002260 | 0.89 | L3MBTL1 (0.85) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1119369 | 0.89 | ALDH1A1 (0.82) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28912823 | 0.89 | ALDH1A1 (0.82) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1000557 | 0.89 | ALDH1A1 (1.00) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1095203 | 0.89 | ALDH1A1 (1.00) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22062413 | 0.88 | MEN1 (0.78) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13532172 | 0.88 | KMT2A (0.76) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13532150 | 0.88 | SIRT2 (0.81) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7821199 | 0.88 | SMN1; SMN2 (0.84) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280001-B1 | LONG-CHAIN FATTY ACID ELONGATION ENZYME INHIBITOR COMPRISING ARYLSULFONYL DERIVATIVE AS ACTIVE INGREDIENT | MSD KK (JP) | 2014-10-15 | — | — | EP | disclosed |
| US-8420823-B2 | Long-chain fatty acyl elongase inhibitor comprising arylsulfonyl derivative as active ingredient | MSD K.K. (JP) | 2013-04-16 | — | — | US | disclosed |
| EP-2280001-A1 | LONG-CHAIN FATTY ACID ELONGATION ENZYME INHIBITOR COMPRISING ARYLSULFONYL DERIVATIVE AS ACTIVE INGREDIENT | Banyu Pharmaceutical Co., Ltd. (JP) | 2011-02-02 | — | — | EP | disclosed |
| US-20110009622-A1 | LONG-CHAIN FATTY ACYL ELONGASE INHIBITOR COMPRISING ARYLSULFONYL DERIVATIVE AS ACTIVE INGREDIENT | MSD K.K. (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20100016310-A1 | METHODS OF USING ARYL SULFONYL COMPOUNDS EFFECTIVE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| WO-2008022171-A1 | METHODS OF USING ARYL SULFONYL COMPOUNDS EFFECTIVE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009622-A1 | LONG-CHAIN FATTY ACYL ELONGASE INHIBITOR COMPRISING ARYLSULFONYL DERIVATIVE AS ACTIVE INGREDIENT | ELOVL1, ELOVL6, ELOVL3 | L3MBTL1 511/4885MEN1 4600/4885KMT2A 473/4885 |
| US-20100016310-A1 | METHODS OF USING ARYL SULFONYL COMPOUNDS EFFECTIVE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, EPHX2, NCEH1 | L3MBTL1 3743/4885MEN1 4563/4885KMT2A 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.