Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10017087 | 0.81 | NISCH (0.42) | MAPTNISCHNOTUMGAAKDM4E | |
| SCHEMBL23018489 | 0.68 | MAOA (0.42) | MAPTLMNAPDPK1KDM4ECYP3A4 | |
| SCHEMBL8458131 | 0.67 | KDM4E (0.46) | MAPTLMNANISCHTP53PKM | |
| SCHEMBL2173463 | 0.65 | KDR (0.51) | MAPTLMNANOTUMMAPK14KDR | |
| Dihydronicotyrine SCHEMBL1207625 | 0.64 | CYP2A6 (0.52) | MAPTLMNANISCHTP53KDM4E | |
| SCHEMBL17549801 | 0.64 | LMNA (0.42) | MAPTLMNANISCHNOTUMPDPK1 | |
| SCHEMBL27359997 | 0.62 | MAPT (0.53) | MAPTLMNANISCHNOTUMPDPK1 | |
| SCHEMBL9728 | 0.61 | MAPT (1.00) | MAPTLMNANOTUMPDPK1GAA | |
| SCHEMBL4790041 | 0.61 | ADRA2A (0.56) | MAPTLMNANISCHPKN2 | |
| SCHEMBL22673876 | 0.60 | LMNA (0.37) | MAPTLMNANISCHNOTUMPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012005214-A1 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | JNC株式会社 (JP) | 2012-01-12 | — | — | WO | disclosed |