Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18510837 | 1.00 | LMNA (0.41) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL14769876 | 0.88 | LMNA (0.40) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL10017441 | 0.87 | LGALS9 (0.38) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL2692294 | 0.86 | ALDH1A1 (0.46) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL6369092 | 0.86 | ALDH1A1 (0.46) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL16756809 | 0.86 | ALDH1A1 (0.46) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL13607676 | 0.86 | ALDH1A1 (0.46) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL1030464 | 0.86 | ALDH1A1 (0.46) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL18510829 | 0.86 | LGALS9 (0.38) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL13170885 | 0.86 | LGALS9 (0.38) | LMNALGALS9LGALS1LGALS3LGALS7; LGALS7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765933-B2 | Asynthesis of β-nucleosides | PHARMAESSENTIA CORP. (TW) | 2014-07-01 | — | — | US | disclosed |
| US-20120259106-A1 | ASYNTHESIS OF B-NUCLEOSIDES | PHARMAESSENTIA CORP. (TW) | 2012-10-11 | — | — | US | disclosed |
| US-8193339-B2 | Synthesis of β-nucleosides | PHARMAESSENTIA CORP. (TW) | 2012-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120259106-A1 | ASYNTHESIS OF B-NUCLEOSIDES | ATIC, DPYD, DUT | LMNA 1506/4885LGALS9 4392/4885LGALS1 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.