SCHEMBL10017461

SCHEMBL10017461

COc1ccc(Cc2ccc(/C=C/C(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.83
CYP3A4 P08684 1/20 0.83
NFKB1 P19838 1/20 0.83
NFKB2 Q00653 1/20 0.83
RELA Q04206 1/20 0.83
MAOB P27338 8/20 0.74
MAPT P10636 5/20 0.74
KMT2A Q03164 3/20 0.74
MEN1 O00255 2/20 0.74
ALDH1A1 P00352 2/20 0.74
CYP1B1 Q16678 2/20 0.74
HSPD1 P10809 1/20 0.74
TNFRSF1A P19438 1/20 0.74
HSPE1 P61604 1/20 0.74
F3 P13726 2/20 0.70
XDH P47989 2/20 0.68
RAB9A P51151 2/20 0.64
NPC1 O15118 2/20 0.64
MAOA P21397 3/20 0.63
P4HB P07237 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017446 0.96 BCHE (0.77) BCHECYP3A4NFKB1NFKB2RELA
4-Methoxy Chalcone SCHEMBL9338705 0.91 BCHE (1.00) BCHECYP3A4NFKB1NFKB2RELA
4-Methoxy Chalcone SCHEMBL1566431 0.91 BCHE (1.00) BCHECYP3A4NFKB1NFKB2RELA
4-Methoxy Chalcone SCHEMBL521906 0.91 BCHE (1.00) BCHECYP3A4NFKB1NFKB2RELA
SCHEMBL10017455 0.87 BCHE (0.91) BCHECYP3A4NFKB1NFKB2RELA
SCHEMBL27977337 0.87 BCHE (0.91) BCHECYP3A4NFKB1NFKB2RELA
4'-Methoxychalcone SCHEMBL3698834 0.87 MAOB (0.97) BCHECYP3A4NFKB1NFKB2RELA
4'-Methoxychalcone SCHEMBL3698831 0.87 MAOB (0.97) BCHECYP3A4NFKB1NFKB2RELA
SCHEMBL11999068 0.86 CYP3A4 (0.62) BCHECYP3A4NFKB1NFKB2RELA
SCHEMBL18972861 0.86 BCHE (0.88) BCHECYP3A4NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9541795-B2 Liquid crystal display device and method for manufacturing the same SONY CORPORATION (JP) 2017-01-10 US disclosed
US-9523889-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-12-20 US disclosed
US-9507210-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-11-29 US disclosed
US-9470929-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-10-18 US disclosed
US-9465244-B2 Liquid crystal display SONY CORPORATION (JP) 2016-10-11 US disclosed
US-9366910-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-06-14 US disclosed
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2016-01-14 US disclosed
US-9235084-B2 Liquid crystal display device and manufacturing method thereof SONY CORPORATION (JP) 2016-01-12 US disclosed
US-9146425-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2015-09-29 US disclosed
US-20150146148-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2015-05-28 US disclosed
US-20140170926-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2014-06-19 US disclosed
US-20140168588-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME SONY CORPORATION (JP) 2014-06-19 US disclosed
US-20140111752-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2014-04-24 US disclosed
US-20140071390-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2014-03-13 US disclosed
US-20130010244-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION 2013-01-10 US disclosed
US-20120212691-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-08-23 US disclosed
US-20120026440-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME SONY CORPORATION (JP) 2012-02-02 US disclosed
US-20110273652-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-11-10 US disclosed
US-20110157531-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-06-30 US disclosed
US-20110134382-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND LIQUID CRYSTAL DISPLAY DEVICE SONY CORPORATION (JP) 2011-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME PYM1, PDCD2L, SDAD1 BCHE 3203/4885CYP3A4 2921/4885NFKB1 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.