SCHEMBL1001806

SCHEMBL1001806

O=Nc1cc(F)c(O)cc1O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CA3 P07451 1/20 0.36
▸ CA6 P23280 1/20 0.36
▸ CA5A P35218 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ CA14 Q9ULX7 1/20 0.36
▸ CA5B Q9Y2D0 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ GRIN2D O15399 1/20 0.30
▸ GRIN3B O60391 1/20 0.30
▸ GRIN1 Q05586 1/20 0.30
▸ GRIN2A Q12879 1/20 0.30
▸ GRIN2B Q13224 1/20 0.30
▸ GRIN2C Q14957 1/20 0.30
▸ GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14980798 0.76 HTT (0.35) LMNAHSD17B10
SCHEMBL24817709 0.76 IDO1 (0.30) —
SCHEMBL16377542 0.76 — —
SCHEMBL9296093 0.73 ESR1 (0.38) KDM4ELMNAHSD17B10
SCHEMBL5511692 0.73 CA9 (0.50) CA3CA6CA5ACA9CA14
SCHEMBL21635507 0.72 CYP3A4 (0.35) KDM4E
SCHEMBL13466234 0.72 — —
SCHEMBL9819938 0.71 ALOX15 (0.36) KDM4E
SCHEMBL9820018 0.71 MAPT (0.42) KDM4ELMNAHSD17B10GRIN2DGRIN3B
SCHEMBL1005024 0.71 TSHR (0.46) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2298312-B1 Fluorinated resorufin compounds and their application in detecting hydrogen peroxide MOLECULAR PROBES INC (US) 2018-09-26 — — EP disclosed
US-20170037248-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation 2017-02-09 — — US disclosed
US-20170037248-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation 2017-02-09 — — US disclosed
US-20170037248-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation 2017-02-09 — — US disclosed
US-9212385-B2 Fluorinated resorufin compounds and their application Life Technologies Corporation (US) 2015-12-15 — — US disclosed
US-9212385-B2 Fluorinated resorufin compounds and their application Life Technologies Corporation (US) 2015-12-15 — — US disclosed
EP-1685117-B1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION IN DETECTING HYDROGEN PEROXIDE LIFE TECHNOLOGIES CORP (US) 2015-01-07 — — EP disclosed
US-20140220612-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation (US) 2014-08-07 — — US disclosed
US-20140220612-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation (US) 2014-08-07 — — US disclosed
US-20140220612-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION Life Technologies Corporation (US) 2014-08-07 — — US disclosed
US-7875261-B2 Fluorinated resorufin compounds and their application Life Technologies Corporation (US) 2011-01-25 — — US disclosed
US-7432372-B2 for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-10-07 — — US disclosed
US-7432372-B2 for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-10-07 — — US disclosed
US-7432372-B2 for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-10-07 — — US disclosed
US-20080113341-A1 Staining; for detecting reactive oxygen species such as hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-05-15 — — US disclosed
US-20080113341-A1 Staining; for detecting reactive oxygen species such as hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-05-15 — — US disclosed
US-20080113341-A1 Staining; for detecting reactive oxygen species such as hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays INVITROGEN CORPORATION (US) 2008-05-15 — — US disclosed
EP-1685117-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION IN DETECTING HYDROGEN PEROXIDE Molecular Probes Inc. (US) 2006-08-02 — — EP disclosed
WO-2005042504-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION IN DETECTING HYDROGEN PEROXIDE MOLECULAR PROBES, INC. (US) 2005-05-12 — — WO disclosed
US-20050096315-A1 for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays Life Technologies Corporation 2005-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037248-A1 FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION CYP2F1, CYP4F2, CYP4F3 CA3 4452/4885CA6 4063/4885CA5A 1914/4885
US-20050096315-A1 for detecting reactive oxygen species, e.g., hydrogen peroxide; used in immunology, diagnostics, molecular biology and fluorescence based assays GPX4, PRDX3, MPO CA3 3692/4885CA6 2898/4885CA5A 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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