Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875444 | 0.86 | TSHR (0.52) | TSHRHSD17B10HPGDHSP90AA1CYP3A4 | |
| SCHEMBL4925884 | 0.80 | HSD17B10 (0.41) | TSHRHSD17B10HPGDHSP90AA1CYP3A4 | |
| SCHEMBL28187718 | 0.76 | HTR3E (0.38) | CA2CA1 | |
| SCHEMBL69259 | 0.73 | HSD17B10 (0.80) | TSHRHSD17B10HPGDHSP90AA1CYP3A4 | |
| SCHEMBL28187032 | 0.72 | PGK1 (0.36) | — | |
| SCHEMBL1001806 | 0.71 | CA3 (0.36) | HSD17B10 | |
| SCHEMBL9819938 | 0.71 | ALOX15 (0.36) | HSP90AA1 | |
| SCHEMBL9820018 | 0.71 | MAPT (0.42) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 | |
| SCHEMBL13636128 | 0.70 | SRC (0.37) | HSD17B10HPGDALDH1A1TDP1 | |
| SCHEMBL25704899 | 0.70 | KDM4E (0.34) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10401361-B2 | Intracellular organelle peptide targeted enzyme substrates | MARKER GENE TECHNOLOGIES, INC. (US) | 2019-09-03 | — | — | US | disclosed |
| EP-2298312-B1 | Fluorinated resorufin compounds and their application in detecting hydrogen peroxide | MOLECULAR PROBES INC (US) | 2018-09-26 | — | — | EP | disclosed |
| US-20180120317-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | MARKER GENE TECHNOLOGIES, INC. | 2018-05-03 | — | — | US | disclosed |
| US-9841426-B2 | Intracellular organelle peptide targeted enzyme substrates | MARKER GENE TECHNOLOGIES, INC (US) | 2017-12-12 | — | — | US | disclosed |
| US-9677115-B2 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20170037248-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation | 2017-02-09 | — | — | US | disclosed |
| US-20170037248-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation | 2017-02-09 | — | — | US | disclosed |
| US-20170037248-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | Life Technologies Corporation | 2017-02-09 | — | — | US | disclosed |
| US-9212385-B2 | Fluorinated resorufin compounds and their application | Life Technologies Corporation (US) | 2015-12-15 | — | — | US | disclosed |
| US-9212385-B2 | Fluorinated resorufin compounds and their application | Life Technologies Corporation (US) | 2015-12-15 | — | — | US | disclosed |
| US-5773236-A | FLUORESCENT DYES FOR DETECTION OF ENZYMES FOR METABOLISM IN CELLS | MOLECULE PROBES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| US-5304645-A | Colored or fluorescent labels | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| EP-0210559-B1 | N-ACYLDIHYDRORESORUFIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AS WELL AS THEIR USE FOR THE DETERMINATION OF HYDROGEN PEROXIDE, PEROXIDATICALLY ACTIVE COMPOUNDS, OR PEROXIDASE | Roche Diagnostics GmbH (DE) | 1991-09-25 | — | — | EP | disclosed |
| EP-0156347-B1 | GLYCOSIDES OF RESOFURIN DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE IN THE DETERMINATION OF THE ACTIVITY OF GLYCOSIDASES | Roche Diagnostics GmbH (DE) | 1991-09-04 | — | — | EP | disclosed |
| US-4954630-A | COLORIMETRIC OR FLUORESCENT ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-09-04 | — | — | US | disclosed |
| EP-0209875-B1 | RESORUFIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1990-08-29 | — | — | EP | disclosed |
| US-4737466-A | N-acyldihydroresorufin derivatives, processes for their preparation, reagents containing them and the use thereof for determining hydrogen peroxide, peroxidate-acting compounds or peroxidase | BOEHRINGER MANNHEIM GMBH (DE) | 1988-04-12 | — | — | US | disclosed |
| EP-0210559-A2 | N-Acyldihydroresorufin derivatives, process for their preparation as well as their use for the determination of hydrogen peroxide, peroxidatically active compounds, or peroxidase | Roche Diagnostics GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209875-A1 | Resorufin derivatives and process for their preparation | Roche Diagnostics GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0156347-A2 | Glycosides of resofurin derivatives, method for their preparation and their use in the determination of the activity of glycosidases | Roche Diagnostics GmbH (DE) | 1985-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10401361-B2 | Intracellular organelle peptide targeted enzyme substrates | GLG1, GBA3, MIA3 | TSHR 3899/4885HSD17B10 676/4885HPGD 1364/4885 |
| US-20170037248-A1 | FLUORINATED RESORUFIN COMPOUNDS AND THEIR APPLICATION | CYP2F1, CYP4F2, CYP4F3 | TSHR 2823/4885HSD17B10 325/4885HPGD 649/4885 |
| US-20180120317-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | GLG1, GBA3, MIA3 | TSHR 3899/4885HSD17B10 676/4885HPGD 1364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.