Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 2/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018489 | 0.88 | ADH5 (0.34) | HTTALDH1A1MEN1KMT2AMCL1 | |
| SCHEMBL10018484 | 0.85 | RXFP1 (0.37) | HTTHDAC2ALDH1A1MEN1KMT2A | |
| SCHEMBL16482337 | 0.82 | RPS6KA3 (0.41) | HTTALDH1A1MEN1KMT2ANCOA1 | |
| SCHEMBL10018491 | 0.81 | HTR7 (0.37) | HTTBRD4DGAT2MGAT2 | |
| SCHEMBL16482012 | 0.80 | MEN1 (0.38) | HTTALDH1A1MEN1KMT2A | |
| SCHEMBL16482061 | 0.79 | PRKCI (0.44) | HTTMGAT2 | |
| SCHEMBL13098376 | 0.79 | AOC3 (0.36) | HTTALDH1A1 | |
| SCHEMBL10018488 | 0.78 | CYP19A1 (0.33) | HTTALDH1A1CMA1 | |
| SCHEMBL16482132 | 0.78 | MGAT2 (0.52) | DGAT2MGAT2 | |
| SCHEMBL5028258 | 0.77 | CYP19A1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101699-B2 | Electron-transporting polymers | GENERAL ELECTRIC COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100137538-A1 | ELECTRON-TRANSPORTING POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2010-06-03 | — | — | US | disclosed |