Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018484 | 0.95 | RXFP1 (0.37) | ADH5DYRK1AGSK3BNFATC1RAB9A | |
| SCHEMBL10018482 | 0.88 | HTT (0.35) | KMT2AHTTMEN1ALDH1A1MCL1 | |
| SCHEMBL261834 | 0.84 | RXFP1 (0.40) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL13098376 | 0.81 | AOC3 (0.36) | ADH5DYRK1AGSK3BNFATC1HTT | |
| SCHEMBL10018488 | 0.81 | CYP19A1 (0.33) | DYRK1AGSK3BNFATC1HTTALDH1A1 | |
| SCHEMBL5028258 | 0.80 | CYP19A1 (0.38) | ALDH1A1CYP17A1AOC3 | |
| SCHEMBL14424740 | 0.80 | MAOA (0.42) | ADH5DHODHCYP17A1AOC3 | |
| SCHEMBL12383089 | 0.78 | RXFP1 (0.47) | GSK3BRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL10018487 | 0.78 | ADH5 (0.36) | ADH5DYRK1AGSK3BNFATC1HTT | |
| SCHEMBL10018486 | 0.76 | MAOA (0.41) | HTTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101699-B2 | Electron-transporting polymers | GENERAL ELECTRIC COMPANY (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100137538-A1 | ELECTRON-TRANSPORTING POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2010-06-03 | — | — | US | disclosed |