SCHEMBL516018

SCHEMBL516018

CCCCn1c(=O)c2c(ncn2C)n(C)c1=O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 4/20 0.78
PDE4B Q07343 4/20 0.78
PDE4C Q08493 4/20 0.78
PDE4D Q08499 4/20 0.78
ADORA2A P29274 3/20 0.78
ADORA2B P29275 7/20 0.69
TNF P01375 4/20 0.69
CYP1A2 P05177 2/20 0.69
PMP22 Q01453 2/20 0.69
USP2 O75604 1/20 0.69
LMNA P02545 1/20 0.69
TSHR P16473 1/20 0.69
NFKB1 P19838 1/20 0.69
ACHE P22303 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
RXFP1 Q9HBX9 1/20 0.69
BLM P54132 2/20 0.68
CYP3A4 P08684 1/20 0.68
HSD17B10 Q99714 1/20 0.68
CHIT1 Q13231 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL266179 0.95 PDE4A (0.72) PDE4APDE4BPDE4CPDE4DADORA2A
SCHEMBL27348729 0.94 PDE4A (0.70) PDE4APDE4BPDE4CPDE4DADORA2A
SCHEMBL23144749 0.94 PDE4A (0.70) PDE4APDE4BPDE4CPDE4DADORA2A
Pentifylline SCHEMBL147256 0.94 PDE4A (0.70) PDE4APDE4BPDE4CPDE4DADORA2A
SCHEMBL27334771 0.94 PDE4A (0.70) PDE4APDE4BPDE4CPDE4DADORA2A
Bisdionin D SCHEMBL16120988 0.92 ADORA2B (0.79) PDE4APDE4BPDE4CPDE4DADORA2A
Bisdionin C SCHEMBL10018600 0.92 CHIT1 (0.75) PDE4APDE4BPDE4CPDE4DADORA2A
SCHEMBL16120981 0.91 ADORA2B (0.77) PDE4APDE4BPDE4CPDE4DADORA2A
SCHEMBL315740 0.91 ADORA2B (0.82) PDE4APDE4BPDE4CPDE4DADORA2A
Pentifylline SCHEMBL4779804 0.90 ADORA2B (0.65) PDE4APDE4BPDE4CPDE4DADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0167566-A4 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. SUNSHINE ABRAHAM (US) 1987-06-29 EP claimed
EP-0165308-A4 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. RICHARDSON VICKS INC (US) 1986-05-16 EP claimed
US-4567183-A SYNERGISTIC, POTENTIATION ANALGESIC ASSOCIATES (US) 1986-01-28 US claimed
EP-0167566-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME SUNSHINE, Abraham (US) 1986-01-15 EP claimed
EP-0165308-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. RICHARDSON VICKS INC (US) 1985-12-27 EP claimed
US-4558051-A Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same RICHARDSON-VICKS, INC. (US) 1985-12-10 US claimed
WO-1985002540-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME RICHARDSON-VICKS, INC. (US) 1985-06-20 WO claimed
WO-1985002542-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME SUNSHINE ABRAHAM 1985-06-20 WO claimed
US-20260117148-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2026-04-30 US disclosed
US-20250386846-A1 Food Compositions Including Aragonite NANT HOLDINGS IP LLC (US) 2025-12-25 US disclosed
US-20250320430-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2025-10-16 US disclosed
US-12419336-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2025-09-23 US disclosed
WO-2025134877-A1 KIT AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2025-06-26 WO disclosed
US-20250194654-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2025-06-19 US disclosed
US-4567183-A SYNERGISTIC, POTENTIATION ANALGESIC ASSOCIATES (US) 1986-01-28 US disclosed
EP-0167566-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME SUNSHINE, Abraham (US) 1986-01-15 EP disclosed
EP-0165308-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. RICHARDSON VICKS INC (US) 1985-12-27 EP disclosed
US-4558051-A Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same RICHARDSON-VICKS, INC. (US) 1985-12-10 US disclosed
WO-1985002540-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME RICHARDSON-VICKS, INC. (US) 1985-06-20 WO disclosed
WO-1985002542-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME SUNSHINE ABRAHAM 1985-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117148-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE TPMT, P2RY13, TST PDE4A 3690/4885PDE4B 3968/4885PDE4C 3394/4885
US-20250386846-A1 Food Compositions Including Aragonite PLCG2, PLCG1, PLCB3 PDE4A 3601/4885PDE4B 3149/4885PDE4C 2886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.